TOP 200 DRUGS Flashcards
Diclofenac
NSAID→Acetic acids
RA, OA, Ankylosing spondylitis
Trazadone
Newer Antidepressants
TX depression and sedative (migraine prevention)
Ropinirole
Parkinson’s
TX Parkinson disease (monotherapy for early, adjunct tx for advanced)
Aspirin
NSAID→Salicylate
Prophylactically: DEC incidence of CVD (MI, unstable angina)
LOW DOSE: Antipyretic, Analgesic
HIGH DOSE: Anti-inflammatory
Chronic usage: CA prevention
Ferrous sulfate
TX iron deficiency anemia
Lamotrigine
Epilepsy→Prolonged inactivation of VG Na+ channels
TX absence seizure
ADJUNCT TX Focal seizures (adults and children >2Y/O), Generalized seizures
Topiramate
Epilepsy
ADJUNCT TX Focal seizures
Divalproex sodium
Anticonvulsant
PROPHYLAXIS: Migraine
Azithromycin
ABX→Macrolides
Similiar to Erythromycin
- < Strep and staph coverage
- > Atypical mycobacterial and H. influenzae
Gabapentin
Epilepsy
TX (newly diagnosed) Focal seizures, and peripheral neuropathy
ADJUNCT TX Refractory seizures
Acyclovir
Antivirals→Guanosine analogs
TX HSV infection
Morphine
OPIATE→Strong Agonist
Clindamycin
ABX→Lincosamides
TX Anaerobic or polymicrobial infections
Sumatriptan
HA→Triptan (Migraine-specific)
TX 1st LINE moderate/severe migraine
Phenytoin
Epilepsy→Prolonged inactivation of VG Na+ channels
TX focal/generalized seizures, Status epilepticus
Folic Acid
TX megaloblastic anemias
(pregnancy protection against neural tube defect)
Calcium
TX hypocalcemia
Valacyclovir
Antivirals→Guanosine analogs
TX HSV infection
Sulfamethoxazole/Trimethoprim
ABX→Sulfonamides
TX Pneumocystis carinii, Bacterial diarrhea
2nd LINE TX CAP, UTI, prostatitis, Acute otitis media
PROPHYLAXIS UTI
Meloxicam
NSAID→Oxicam (dose dependent)
TX Arthritis
Doxycycline
ABX→Inhibition of RNA/DNA synthesis→30s→Tetracycline
TX multi-drug regimen for anthrax, chlamydia, cervicitis, urethritis, CAP, Lyme disease, chronic prostatitis, sinusitis, PID, acne, rosacea, rickettsia infection
Ergocalciferol
TX hypocalcemia, Vitamin D deficiency, postmenopausal osteoporsis, renal failure
Magnesium
Anticonvulsant
TX immediate control of life-threatening convulsions in severe toxemia (pregnancy-related), acute nephritis (children), electrolyte replacement (hypomagnesia)
Hydrocodone Bitartrate/Acetaminophen
OPIATE→Mild/Moderate Agonist
TX pain relief (less efficacious than morphine, given with ASA and APAP)
Ibuprofen
NSAID→Propionic Acid
MSK and joint pain, mild/moderate analgesia, fever relief
Tramadol
OPIATE> Weak agonist (Blocks reuptake of serotonin and NE)
TX pain relief
Acetaminophen
NSAID
Antipyretic, anti-inflammatory (weak), analgesic (NO antiplatelet effects)
Levetiracetam
Epilepsy
TX Focal, Generalized seizures
Levofloxacin
ABX→Quinolones (Fluoroquinolones)
TX Inhalation anthrax infection
Zolpidem
GABA agonist→Benzodiazepine
TX Sleep enhancers (insomina)
Celecoxib
NSAID→COX-2 inhibitor
TX RA, OA, AS, juvenile RA, acute pain (adults)
Fluconazole
Antifungal→Azoles Triazole
TX vaginal candidasis
Oxycodone
OPIATE→Mild/Moderate Agonist
TX pain relief (less efficacious than morphine, given with ASA and APAP)
Hydroxychloroquine sulfate
RA→DMARDs (Nonbiologic)
TX RA, antimalarial (mild disease/combination, reserved for RA unresponsive to NSAIDs - not 1st lINE)
Oxcarbazepine
Epilepsy
TX Focal, secondarily generalized (tonic-clonic) seizure
Nystatin
Antifungal→Polyene ABX
TX candidiasis (skin, mucous membrane)
Ciprofloxacin
ABX→Quinolones (fluoroquinolones)
PROPHYLAXIS Anthrax (post-exposure)
Benztropine
Muscarinic agonist
TX Parkinson disease
Amoxicillin
ABX→Inhibition of Cell Wall Synthesis→Penicilin→Aminopenicillin
TX URI (sinusitis, otitis), UTI (uncomplicated), meningitis, salmonella spp. (NOT 1st LINE)
BACTERIA Gram-negative cocci, Enterobacterialacase (NOT Treponema spp. Actinomyces spp.)
Pregabalin
Epilepsy
ADJUNCT TX focal onset seizures, peripheral neuropathy, postherpetic neuralgia, fibromyalgia
Naproxen
NSAID→Propionic Acid
Similiar to Ibuprofen (MSK/joint pain, mild/moderate analgesia, fever relief)
