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Pharm I: Exam 3 > TOP 200 DRUGS > Flashcards

TOP 200 DRUGS Flashcards

1
Q

Diclofenac

A

NSAID→Acetic acids

RA, OA, Ankylosing spondylitis

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2
Q

Trazadone

A

Newer Antidepressants

TX depression and sedative (migraine prevention)

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3
Q

Ropinirole

A

Parkinson’s

TX Parkinson disease (monotherapy for early, adjunct tx for advanced)

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4
Q

Aspirin

A

NSAID→Salicylate

Prophylactically: DEC incidence of CVD (MI, unstable angina)

LOW DOSE: Antipyretic, Analgesic

HIGH DOSE: Anti-inflammatory

Chronic usage: CA prevention

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5
Q

Ferrous sulfate

A

TX iron deficiency anemia

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6
Q

Lamotrigine

A

Epilepsy→Prolonged inactivation of VG Na+ channels

TX absence seizure

ADJUNCT TX Focal seizures (adults and children >2Y/O), Generalized seizures

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7
Q

Topiramate

A

Epilepsy

ADJUNCT TX Focal seizures

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8
Q

Divalproex sodium

A

Anticonvulsant

PROPHYLAXIS: Migraine

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9
Q

Azithromycin

A

ABX→Macrolides

Similiar to Erythromycin

  • < Strep and staph coverage
  • > Atypical mycobacterial and H. influenzae
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10
Q

Gabapentin

A

Epilepsy

TX (newly diagnosed) Focal seizures, and peripheral neuropathy

ADJUNCT TX Refractory seizures

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11
Q

Acyclovir

A

Antivirals→Guanosine analogs

TX HSV infection

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12
Q

Morphine

A

OPIATE→Strong Agonist

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13
Q

Clindamycin

A

ABX→Lincosamides

TX Anaerobic or polymicrobial infections

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14
Q

Sumatriptan

A

HA→Triptan (Migraine-specific)

TX 1st LINE moderate/severe migraine

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15
Q

Phenytoin

A

Epilepsy→Prolonged inactivation of VG Na+ channels

TX focal/generalized seizures, Status epilepticus

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16
Q

Folic Acid

A

TX megaloblastic anemias

(pregnancy protection against neural tube defect)

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17
Q

Calcium

A

TX hypocalcemia

18
Q

Valacyclovir

A

Antivirals→Guanosine analogs

TX HSV infection

19
Q

Sulfamethoxazole/Trimethoprim

A

ABX→Sulfonamides

TX Pneumocystis carinii, Bacterial diarrhea

2nd LINE TX CAP, UTI, prostatitis, Acute otitis media

PROPHYLAXIS UTI

20
Q

Meloxicam

A

NSAID→Oxicam (dose dependent)

TX Arthritis

21
Q

Doxycycline

A

ABX→Inhibition of RNA/DNA synthesis→30s→Tetracycline

TX multi-drug regimen for anthrax, chlamydia, cervicitis, urethritis, CAP, Lyme disease, chronic prostatitis, sinusitis, PID, acne, rosacea, rickettsia infection

22
Q

Ergocalciferol

A

TX hypocalcemia, Vitamin D deficiency, postmenopausal osteoporsis, renal failure

23
Q

Magnesium

A

Anticonvulsant

TX immediate control of life-threatening convulsions in severe toxemia (pregnancy-related), acute nephritis (children), electrolyte replacement (hypomagnesia)

24
Q

Hydrocodone Bitartrate/Acetaminophen

A

OPIATE→Mild/Moderate Agonist

TX pain relief (less efficacious than morphine, given with ASA and APAP)

25
Q

Ibuprofen

A

NSAID→Propionic Acid

MSK and joint pain, mild/moderate analgesia, fever relief

26
Q

Tramadol

A

OPIATE> Weak agonist (Blocks reuptake of serotonin and NE)

TX pain relief

27
Q

Acetaminophen

A

NSAID

Antipyretic, anti-inflammatory (weak), analgesic (NO antiplatelet effects)

28
Q

Levetiracetam

A

Epilepsy

TX Focal, Generalized seizures

29
Q

Levofloxacin

A

ABX→Quinolones (Fluoroquinolones)

TX Inhalation anthrax infection

30
Q

Zolpidem

A

GABA agonist→Benzodiazepine

TX Sleep enhancers (insomina)

31
Q

Celecoxib

A

NSAID→COX-2 inhibitor

TX RA, OA, AS, juvenile RA, acute pain (adults)

32
Q

Fluconazole

A

Antifungal→Azoles Triazole

TX vaginal candidasis

33
Q

Oxycodone

A

OPIATE→Mild/Moderate Agonist

TX pain relief (less efficacious than morphine, given with ASA and APAP)

34
Q

Hydroxychloroquine sulfate

A

RA→DMARDs (Nonbiologic)

TX RA, antimalarial (mild disease/combination, reserved for RA unresponsive to NSAIDs - not 1st lINE)

35
Q

Oxcarbazepine

A

Epilepsy

TX Focal, secondarily generalized (tonic-clonic) seizure

36
Q

Nystatin

A

Antifungal→Polyene ABX

TX candidiasis (skin, mucous membrane)

37
Q

Ciprofloxacin

A

ABX→Quinolones (fluoroquinolones)

PROPHYLAXIS Anthrax (post-exposure)

38
Q

Benztropine

A

Muscarinic agonist

TX Parkinson disease

39
Q

Amoxicillin

A

ABX→Inhibition of Cell Wall Synthesis→Penicilin→Aminopenicillin

TX URI (sinusitis, otitis), UTI (uncomplicated), meningitis, salmonella spp. (NOT 1st LINE)

BACTERIA Gram-negative cocci, Enterobacterialacase (NOT Treponema spp. Actinomyces spp.)

40
Q

Pregabalin

A

Epilepsy

ADJUNCT TX focal onset seizures, peripheral neuropathy, postherpetic neuralgia, fibromyalgia

41
Q

Naproxen

A

NSAID→Propionic Acid

Similiar to Ibuprofen (MSK/joint pain, mild/moderate analgesia, fever relief)

Pharm I: Exam 3 (10 decks)

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