Top 200 Flashcards
ADRs w/ glimepiride
weight gain
edema
C/I w/ sulfaonylureas
getstation DM or T1DM
MOA of sulfonylureas
stimulates insulin release from Beta cells
Drug C/I w/ CrCl <22
Glimepiride
sulfonylurea w/ greater risk of hypoglycemia
glyburide
sulonylurea C/I if CrCl <10
Glipizide
DDP-IV inhibitior, increases insulin synthesis and lower glucose secretion
sitagliptan
lower total LDL and TG
increases HDL
Atorvastatain
rapid acting insulins
Novolog
Humalog
decreases production of HGP and intestinal glucose absorption
Metformin
bisphosphonate
used to tx osteoporosis, paget’s dz, reduce hypercalcemia in tumor-induced bone dz
alendronate
Bisphosphonate given once a month to tx and prevent osteoporosis in postmenopausal women
Ibandronate (Boniva)
Reduces uric acid synthesis
allopurinol
acetylhcolinesterase inhibitior
used for mild-moderate dementia w/ Alzheimers
Donepezil
DOC for hypothyroidism, goiter, chronic
levothyroxine