Tooth Development 2 Flashcards
Transcription Factors
Found in all cells, interact with core promoter region of DNA
Initiate patterns of gene expression important for makor developmental changes, acts on promotors/enhancers
Signalling Molecules
mediate interctions between cells in embryo
cytokines
cell surface receptors
intrinsic protein kinase activity or second messengers
Protooncogene
direct formation of various molecules
oncogene
mutated protooncogene that induces tumor growth
tumor supressor genes
limit cell division
Field theory
transcription factorrs are different in each field, induce specific teeth
Clone theory
a small clone induces the dental lamina to begin tooth development, when clone reaches a certain size the tooth bud is initiated
zone of inhibition
makes it so you dont have too many teeth
Dental Epithelium is inductive during
lamina and bud stage
dental papilla mesenchyme is inductive during
cap and early bell stage