Dentin 1 Flashcards

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1
Q

Composition

A
70- inorganic
20- organic
10- water
HA crystals in flattened rectangular plates 60-70 nm long, 20-30 nm wide, 3-4 nm thick
slightly harder than bone
mesenchymal origin
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2
Q

Organic components of dentine

A

90% collagen (mostly 1 and a little 3, 5)
10% non collagenous proteins
makes the scaffold upon which HA crystals are laid down

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3
Q

non collagenous proteins in dentin

A
Dentin matrix protein 1- DMP1
dentin sialophosphoprotein (DSPP)
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4
Q

DSSP cleaved to

A

DSP DGP and DPP

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5
Q

dentin sialoprotein

A

DSP
proteogycan
expressed in tubules
may act to prevent minerlaization
similar to dmp-1
problems can causae dentinogenesis imperfecta types 2&3
(type one defect in collagen-pulp filled with abnormal dentin)
(type 2 dssp defect, same result)
(type 3 enlarged hypomineralized puld chambers)

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6
Q

DGP

A

dentine glycoprotein

unknown function, possibly biominerlaization

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7
Q

DPP

A

dentin phosphoprotein
binds a lot of Ca 2+, intitates HA formation
attached to collagen
not thought to be glycosylated

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8
Q

dentin pulp complex

A

arises from dental papilla
initial differentiation comes from critical interaction with the IEE
odontoblasts differentiate and fill the acellular zone between IEE and dental papilla
provides vascular support to developing OD

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9
Q

DEJ

A

scalloped to help interlock

shape defines crown shape and keeps dentic directly attached to enamel during loading

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10
Q

von korffs fibers

A

.2 mm collagen type 3 fibers associated with fibronectin

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11
Q

dentin formation

A

extends towards the IEE and developing OD extends tomes fibers (process) into developing matrix and secreting dentin matrix components
starts as predentin then gets mineralized
globular is mantle

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12
Q

tomes fiber

A

what gets left behind by OD- future OD process

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13
Q

stages

A

first globular, secreted matrix vesicles releases matrix crystals
non collagenous matrix proteins regulate sebsequent dentin formation resulting in tubular primary dentin

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14
Q

root dentin

A

hertswig root sheaths initiates odontoblast differentiation

mainly just anatomical differences, mingling of dentin collages with cememntum collagen

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15
Q

primary dentin

A

mantle dentin and initial deposition of circumpulpal dentin

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16
Q

secondary dentin

A

tubular dentin laid down subsequent to root formation, histologically distinct from primary
coronal dentin is sigmoidal

17
Q

tertiary dentin

A

response to insult
reactionary- trauma doesnt damage OD
reparative- trauma damaged OD

18
Q

dentin macrostructure

A

more compact at pulp

surrounded by collars of highly calcified peritubular dentin

19
Q

sclerotic dentin

A

occluded tubules
occurs naturally with age
starts apically and moves coronal

20
Q

interglobular dentin

A

hypomineralized dentin
formed when fusion of mineral containing vesicles fail
can be associated with vitamin D deficiency or flourosis
most common near mantle dentin

21
Q

cyclic depostion of primary dentin

A

4 micrometers a day
every five days or so (20 Micro) there is a noticeably different orientation of collaged (lines of von ebner)
mineralization about 4 micrometers a day
secondary dentin is slower

22
Q

contour lines of owen

A

enhanced lines that indicate diruption of tooth formation (neonatal line)
equivalent to straie of retzius

23
Q

granular layer of tomes

A

root dentin
funny looking dots around roots
gets more granular towards apex
possibly:
a) hypomineralized areas of dentin, similar to interglobular dentin
b) part of looped dentinal tubules (artifact of sectioning)
c) specialized structures which help form d-c junction