Tools for Reviewing the Medical Literature Flashcards

1
Q

Define and describe the purpose of the NCT and DOI numbers

A

National Clinical Trials (NCT): a unique identifier # assigned by clinicaltrials.gov (International committee of Medical Journal Editors) once research protocol is submitted prior to study initiation

the DOI is basically the same thing as the NCT, just a different organization that does it

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2
Q

where can NCT/DOI numbers be found and how can they be utilized?

A

on their respective websites and they can be utilized to determine if a study has been published or not

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3
Q

State the full name and type of test(s) the following checklist can be appropriately used for.

STARD

A

STARD: Standard for the Reporting of Diagnostic Accuracy Studies

Useful for diagnostic studies

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4
Q

State the full name and type of test(s) the following checklist can be appropriately used for.

STROBE-ME

A

STROBE-ME: Strengthening the Reporting of Observational Studies in Epidemiology for Molecular Epidemiology Studies

Useful for ???

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5
Q

State the full name and type of test(s) the following checklist can be appropriately used for.

PRISMA

A

PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses

Useful for “systematic reviews” of multiple randomized trials

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6
Q

State the full name and type of test(s) the following checklist can be appropriately used for.

QUADAS-2

A

QUADAS-2: Quality Assesment of Studies of Diagnostic Accuracy in Systematic Reviews (revised ; 2nd ed.)

Useful for “systematic reviews” of multiple diagnostic studies

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7
Q

State the full name and type of test(s) the following checklist can be appropriately used for.

STREGA

A

STREGA: Strengthening the Reporting of Genetic Association Studies

useful for ????

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8
Q

State the full name and type of test(s) the following checklist can be appropriately used for.

TREND

A

TREND: Transparent Reporting of Evaluations with Non-randomized Designs

Useful for reporting evaluations with non-randomized designs of behavioral and public health interventions

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9
Q

State the full name and type of test(s) the following checklist can be appropriately used for.

REMARK

A

REMARK: reporting Recommendations for Tumor marker Prognostic Studies

Useful for tumor marker prognostic studies

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10
Q

State the full name and type of test(s) the following checklist can be appropriately used for.

GRIPS

A

GRIPS: Genetic Risk Prediction Studies

Useful for genetic risk prediction studies

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11
Q

What is the purpose of the NCT?

A

to reduce publication bias

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12
Q

State all examples of design extension. What checklist is this technically under?

A

Non-inferiority trials

Equivalence Trials

Cluster Trials

CONSORT

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13
Q

define a pragmatic trials purpose AND what it is under

A

a randomized, controlled trial whose purpose is to inform decisions about clinical practice

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14
Q

Cohort, case control, and cross sectional studies are all what types of studies?

A

observational studies

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15
Q

State the full name and type of test(s) the following checklist can be appropriately used for.

CONSORT

A

Consolidated Standards of Reporting Trials

useful for randomized interventional trials

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