Tonicity, Calcium Homeostasis Flashcards
Homeostasis
The normal conditions under which the body systems operate. Must be maintained for survival
What is the blood pH
7.35-7.45, A drop in this pH range can be life threatening.
Fluids comportments
Blood, Plasma, Intracellular, Extracellular, interstitial(tissue). All have different concentrations of ions and proteins within them.
What happens to the pH when the H ion concentration increases or decrease
As H ions increase, the pH decreases and becomes acidic.
As H ions decrease, the pH increases and becomes basic.
What is a buffer?
A buffer has the ability to bind or release H ions in solution to maintain the pH range.
Compare and Contrast Acidosis & Alkalosis
They are both disorders that happen with the excess of acid or base which leads to the failure to remove CO2 and intake O2.
Respiratory Acidosis & Alkalosis
They are issues with excess acid or base due to respiratory failure or ventilation failure in the case of acidosis. Respiratory alkalosis is due to alveolar hyperventilation.
Metabolic acidosis or alkalosis
Can be caused by anything that disrupts the body’s metabolism. Electrolytic disturbances, severe vomiting or diarrhea.
What is the Bicarb Equation
CO2 + H20 EQ H2CO3 EQ H + HCO3
As CO2 leaves, H rushes towards the left and H will decrease and make the solution less acidic.
Failure to remove CO2 makes the solution more acidic due to the H ion still being present.
Treatment for acidosis
Using bicarb is an effective treatment because as you release CO2 you can shift the H concentration to the left which decreases the excess acid concentration and it also helps the lungs release more CO2.
Sodium Potassium Pump
Sodium rushes in ( high outside, low inside)
Potassium wants to stay in (high inside, low outside)
Osmosis & Osmotic pressure
Osmosis is the movement of water across the membrane to restore eq.
Water moves towards the more concentrated area because it has less water.
Osmotic pressure is the force needed to stop water from performing osmosis.
Osmolarity
Osmolarity is the measure of the number of particles per liter of solution. It has to be relative to something else. A to B or B to A.
Make sure to check the units!
Iso-osmotic vs Hyposomotic vs Hyperosmotic
Iso-osmotic when concentrations are equal.
Hyposomotic when the concentration is lower than what is being compared to.
Hyperosmotic when the concentration is higher than what is being compared to.
Osmolarity of NaCl
NaCl will dissociate meaning that for 1 osmole we have 2 molecules ( 1 Na and 1 Cl)
If given molarity, must be converted to osmoles.