Tocolytics and Uterotonics Dosages

Question 1

magnesium sulfate

Answer 1

loading dose 4-6g IV over 20-30 min
infusion 1-2mg/hr.
continued through delivery and up to 24 hours post delivery.

Question 2

magnesium sulfate circumstance and level

Answer 2

normal: 1.8-3mg/dL
tocolytic range: 4-8mg/dL
anticonvulsant: 7-9mg/dL
tendon reflexes abolished: 10-12mg/dL
respiratory depression: >12mg/dL
SA and AV blocks, resp arrest: 15-20mg/dL
apnea: 18mg/dL
cardiac arrest: 25mg/dL

Question 3

nifedipine route of admin

Answer 3

PO or SL

Question 4

oxytocin

Answer 4

20-40units/L of isotonic solution IV over 15-20min

Question 5

methergine

Answer 5

.2mg IM-contractions occur within minutes.

dose may be repeated q15-20min up to .8mg

Question 6

hemabate

Answer 6

250mcg IM directly into myometrium. repeat q15-30min for total dose of 2mg

Question 7

misoprostol

Answer 7

800-1000mcg SL or buccal