Drug Dosages Flashcards
Thiopental
induction: 2.5-5mg/kg
Methohexital
induction: 1-2mg/kg
rectal (pedes): 25mg/kg
infusion: 50-150mcg/kg/min
Midazolam
preop: .02-.04mg/kg
PO: .4-.8mg/kg (admin 30 minutes pre induction)
.2mg/kg IV starts to decrease BP and increase HR. CO not altered
postop sedation: .5-4mg loading dose, 1-7mg/hr gtt
paradoxical vocal cord motion: upper airway obstruction with stridor: .5-1mg
diazepam
.1mg/kg
Flumazenil
initial dose .2mg IV. further doses of .1mg IV given q1min.
.5-1mg will abolish therapeutic effect
propofol
adult dose: 1.5-2.5mcg/kg. decrease this in elderly, increase this in pedes.
IV sedation: 25-100mcg/kg/min infusion
anesthesia maintenance: 100-300mcg/kg/min
antiemetic: 10-15mg IV followed by 10mcg/kg/min infusion
antipruritic: 10mg IV r/t intrathecal opioids, cholestasis
anticonvulsant: 1mg/kg IV
etomidate
induction dose: .2-.4mg/kg IV
induction dose up to .3mg/kg results in minimal SE.
>.45mg/kg results in SE.
ketamine
adult induction: 1-2.5mg/kg IV
IM: 4-8mg/kg (<10min onset)
10mg/kg PO (10-20min onset)
analgesia at sub anesthetic doses: .2-.5mg/kg (somatic >visceral effects)
.5-1mg/kg prior to surgical incision. may be followed by infusion. has a role in preventing hyperalgesia
dexmedetomidine
TIVA: .5-1mcg/kg bolus over 15 minutes
infusion: .2-.7mcg/kg/hr (up to 24 hours)
4mcg bolus for pain, up to 16mcg
.5-2mcg/kg for pain
scolpalamine
preop: .3-.5mg IV/IM
physostigmine
15-60mcg/kg IV and repeat as required
codeine
15mg oral cough suppressant
60mg=650mg ASA
120mg IM=10mg morphine
meperidine
12.5mg IV
fentanyl
1-3mcg/kg prior to induction
1-3mcg/kg intraop for analgesia
50-150mcg/kg for surgical anesthesia
trans mucosal pedes, give 45 min prior to induction
transdermal: for ca, lasts x3d or give 24h prior to operation.
sufentanil
for analgesia: .1-.4mcg/kg
alfentanil
15mcg/kg IV blunts stimulation of laryngoscopy
30mcg/kg IV catecholamine response to noxious stimulation
150-300mcg/kg IV produces unconsciousness (induction).
in combination with inhaled anesthetic, 15-150mcg/kg/hr
naloxone
1-4mcg/kg IV
5mcg/kg/hour can fix depression of ventilation without affecting analgesia
nalmefene
15-25mcg IV until effects achieved (max dose 1mcg/kg)
acetaminophen
PO: 325-650mg q4-6h
Ofrimev: 1g q6h
don’t exceed 4g/24h or 2g/24h for alcoholics
gabapentin
preop 1200mg 1-2h before surgery
600mg q8h x 14 days
toradol (ketorlac)
15mg IV or IM q6h
celebrex (celecoxib)
400mg PO preop, 200mg BID x5d postop
lidocaine
1.5mg/kg bolus IBW
1-2mg/kg/hr infusion
magnesium sulfate
30-50mg/kg bolus
10mg/kg/h infusion
