To draw: AA and derivatives Flashcards
1
Q
δ-aminolevulinic acid
A
- endogenous non-proteinogenic amino acid,
- The first compound in the porphyrin synthesis pathway, the pathway that leads to heme in mammals
- Levulinic acid, or 4-oxopentanoic acid, is an organic compound with the formula CH3C(O)CH2CH2CO2H. It is classified as a keto acid
2
Q
A
δ-aminolevulinic acid
3
Q
histamine
A
4
Q
A
histamine
5
Q
serotonine
A
- Biochemically, the indoleamine molecule derives from the amino acid tryptophan, via the (rate-limiting) hydroxylation of the 5 position on the ring (forming the intermediate 5-hydroxytryptophan), and then decarboxylation to produce serotonin
6
Q
A
serotonine
7
Q
GABA
A
- GABA is primarily synthesized from glutamate via the enzyme glutamate decarboxylase (GAD) with pyridoxal phosphate (the active form of vitamin B6) as a cofactor
- GABA transaminase enzymes catalyze the conversion of 4-aminobutanoic acid (GABA) and 2-oxoglutarate (α-ketoglutarate) into succinic semialdehyde and glutamate. Succinic semialdehyde is then oxidized into succinic acid by succinic semialdehyde dehydrogenase and as such enters the citric acid cycle as a usable source of energy
8
Q
A
GABA
9
Q
dopamine
A
10
Q
A
dopamine
11
Q
acetylcholine
A
12
Q
A
acetylcholine
- name is derived from its chemical structure: it is an ester of acetic acid and choline.
- Choline: (N+(CH3)3)-CH2-CH2-OH
13
Q
triiodothyronine
A
14
Q
A
triiodothyronine
15
Q
thyroxine
A
16
Q
A
thyroxine
17
Q
epinephrine
A
18
Q
A
epinephrine
19
Q
norepinephrine
A
20
Q
A
norepinephrine
21
Q
carnitine
A
22
Q
A
carnitine
23
Q
taurine
A
24
Q
A
taurine
25
Q
glutathione
A
26
Q
A
glutathione
27
Q
DOPA
A