TNM Flashcards
Melanoma
●T0 melanomas have an unknown or completely regressed primary tumor.
●Tis is used for melanoma in situ.
●TX tumors are those in which the tumor thickness cannot be assessed (for example, if the diagnosis was established by curettage).
●T1 is ≤1 mm, with T1a <0.8 mm without ulceration, and T1b <0.8 mm with ulceration or 0.8 to 1.0 mm with or without ulceration.
●T2 is >1.0 to 2.0 mm, which is subdivided into T2a or T2b based upon the absence or presence of ulceration.
●T3 is >2.0 to 4.0 mm, which is subdivided into T3a or T3b based upon the absence or presence of ulceration.
●T4 is >4.0 mm, which is subdivided into T4a or T4b based upon the absence or presence of ulceration if ulceration status is known.
●N1 – One involved lymph node, or in transit, satellite, and/or microsatellite metastases with no tumor-involved nodes. This is subdivided into N1a, N1b, and N1c depending upon the method of detection (clinical versus sentinel node biopsy) and the location of disease.
●N2 – Two or three tumor-involved nodes, or in transit, satellite, and/or microsatellite metastases with one tumor-involved node. This is subdivided into N2a, N2b, and N2c depending upon the method of detection (clinical versus sentinel node biopsy) and the location of disease.
●N3 – Four or more tumor-involved nodes, in transit, satellite, and/or microsatellite metastases with two or more tumor-involved nodes, or any number of matted nodes with or without in transit, satellite, and/or microsatellite metastases. This is subdivided into N3a, N3b, and N3c depending upon the method of detection (clinical versus sentinel node biopsy), whether or not the nodes are matted, and the location of disease.
●M1a – Metastasis to distant skin, subcutaneous, or lymph node sites
●M1b – Lung metastasis
●M1c – Metastasis to other visceral sites, excluding the central nervous system
●M1d – Metastasis to the central nervous system, with or without involvement of other sites
