TNM Flashcards

1
Q

T1 Breast cancer

A

2cm or less (T1 is divided into T1a,b,c; radiation-wise it is not important)

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2
Q

T2 Breast cancer

A

more than 2cm but less than 5cm

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3
Q

T3 Breast cancer

A

more than 5cm

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4
Q

T4 Breast cancer

A

extension to chest wall; inflammatory carcinoma

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5
Q

cN1 Breast cancer

A

mobile ipsilateral Level I, II nodes

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6
Q

pN1 Breast cancer

A

micrometastasis (mi) or metastasis in 1-3 axillary LNs (a) or metastasis in IM LNs (b) pathologically but NOT clinically

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7
Q

The 2b and 3b in LN-Staging

A

the moment you have a 2b or a 3b, think about internal mammary (IM) nodes involvement

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8
Q

cN2a in breast cancer
pN2a in breast cancer

A

cN2a: ipsilateral axillary LN (I, II)
pN2a: 4-9 axillary LNs

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9
Q

cN2b in breast cancer
pN2b in breast cancer

A

cN2b: metastasis to internal mammary LNs only
pN2b: only internal mammary LNs

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10
Q

cN3a in breast cancer
pN3a in breast cancer

A

cN3a: infraclavicular LNs
pN3a: < 10 axillary LNs OR infraclavicular LNs

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11
Q

cN3b in breast cancer
pN3b in breast cancer
pN3c in breast cancer

A

cN3b: ipsilateral internal mammary and axillary LN
pN3b: Internal mammary and axillary LNs
pN3c: ipsilateral supraclavicular LNs

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12
Q

Low Risk breast cancer

A

pT1-2 pN0 (1mic)

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13
Q

Very low risk breast cancer

A

ER-pos, keine Risikofaktoren

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14
Q

Low/medium risk

A

ER-pos mit Risikofaktoren (z.B HER2-pos)
ER-negativ

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15
Q

Lymphnode TNM breast cancer

A
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16
Q

5 main breast cancer subtypes according to St. Gallen consensus?

A

Luminal A: ER und PR positiv, HER2 negativ, Ki-67 niedrig
Luminal B, HER2 negativ: ER positiv, HER2 negativ und Ki-67 hoch oder PR negativ oder niedrig
Luminal B, HER2 positiv: ER positiv, HER2 positiv
HER2-positiv (nicht luminal): ER und PR negativ, HER2 positiv
Triple-negativ: ER, PR und HER2 negativ