Boost

Question 1

RT after BCS: When Boost irradiation (AGO 2023)

Answer 1

Improves local control, no survival benefit.
–>All Premenopausal

–>In Postmenopausal,
if (at least 1 factor)
T2,
G3,
HER2-positive,
Triple negative,
EIC

Question 2

Effect of a boost of 16 Gy on OS and local control for patients with stage I and II breast cancer after BCS

Answer 2

Question 3

Which two studies investigate about moderate hypofractionation with SIB?

Answer 3

RTOG 1005 and IMPORT-HIGH
IMPORT HIGH tested SIB against sequential boost with the aim of reducing treatment duration while maintaining excellent local control and similar or reduced toxicity.

Question 4

RTOG 1005 and IMPORT HIGH

Answer 4