TK1 Flashcards
1
Q
How do neutrophils migrate towards site of infection
A
Marginisation and rolling along the vessel wall
Transfer between endothelial cells
Migrate towards chemostatic stimulus
2
Q
How does endometriosis migrate to colon?
A
3 theories
Regurgitation: retrograde flow of menstrual endometrium
Vascular/lymphatic
Metaplastic: arises directly from coelomic epithelium of pelvis
3
Q
What malignancy occurs in immunosupressed patients>
A
SCC, BCC
Lymphoma
Kaposi sarcoma
4
Q
What is sickle cell disease
A
Hereditary haemoglobinopathy
Mutation in B globin leading to HbS formation
5
Q
Sickle cell risk factor for which conditions?
A
Gallstones
Autosplenectomy
6
Q
What activates intrinsic pathway
A
Vessel injury
7
Q
What activates extrinsic pathway
A
damaged cells -> tissue thromboplastin
