Tissues of the Immune System Flashcards

1
Q

What are the primary/central lymphoid organs?

A

Bone marrow, thymus

This is where lymphocytes acquire immunocompetency

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2
Q

What are the secondary/peripheral lymphoid organs?

A

Lymph nodes, spleen, MALT (mucosa-associated lymphoid tissue)

This is where lymphocytes undergo activation

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3
Q

What do lymphatics contain?

A

Lymph - interstitial fluid, lymphocytes, antigens

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4
Q

What are some cellular components of the lymphatic system?

A

T and B lymphocytes, macrophages, plasma cells, dendritic cells

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5
Q

What cells form the tissue framework of the lymphatic system?

A

Reticular cells form the reticular tissue framework

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6
Q

What are the functions of the lymph node?

A
  • Filtration of lymph
  • Antigen presentation
  • Lymphocyte stimulation and proliferation
  • Plasma cell formation and antibody production
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7
Q

What makes up the cortex of the lymph nodes?

A

Lymphoid follicles, mantle zone, germinal center

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8
Q

What are the parts of a lymph node?

A
  • Cortex
  • Paracortex
  • Medulla
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9
Q

What makes up the medulla of the lymph nodes?

A

Sinuses, cords

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10
Q

How do lymphocytes enter the lymph nodes?

A

Via lymphatics and leaky high endothelial venules

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11
Q

How do lymphocytes reenter circulation from the lymph nodes?

A

Via medullary sinuses

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12
Q

What type of cells can be found in the cortex of lymph nodes?

A

B cells

Lymphoid nodules

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13
Q

What kind of cells can be found in the paracortex of lymph nodes?

A

T cells

Diffuse lymphoid tissue

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14
Q

What type of cells can be found in the medulla of lymph nodes?

A

Both B and T cells

Cords, sinuses

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15
Q

Describe the circulation of lymph through the lymph node

A
  • Lymph in afferent lymphatics enter through the capsule
  • Subcapsular sinus
  • Trabecular sinuses
  • Cortex
  • Paracortex
  • Medullary sinuses
  • Efferent lymphatic at hilum
  • Single efferent lymphatic leaves through hilum

Discontinuous endothelium lines passage

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16
Q
A