Tissue Healing, Scars & Wounds Flashcards
What is a wound?
A disruption of the unity of the skin
Some parts of our body can regenerate after wounds, what are they?
Bone, epidermis, epithelium in GI track, liver, peripheral nerve
Factors influencing wound healing ?
Blood supply/type Heredity Age Smoking Alcohol Infections Systematic disease Diabetes Nutrition Pressure of mechanical disruption. (Moveable joint) Medications
Types of wound healing ?
Primary Closure/Intention
Secondary Closure/Intention
Tertiary/Delayed Primary Closure
Primary Closure/Intention
Sutures, adhesives, staples-wound edges are clean and little to no tissue loss - Keep Dry
Secondary Closure/Intention
Left open to heal via body’s processes, scar formation - KEEP MOIST. (Avulsion/pressure injury).
Wound edges can’t be approximated
Tertiary/Delayed Primary Closure
Poor vascular supply, infection, bleeding does not allow for immediate closure.
Phrases of Wound Healing
Hemostasis
Inflammatory Stage
Proliferation Phase/Fibroplastic
Remodeling or Maturation
What is happening at the Hemostasis Phase?
STOP BLEEDING
Vasoconstriction.
Combination of platelets with collagen forming a cloth.
What is happening at the Inflammation Phase?
CLEAN UP AND REMOVAL ANY DEBRIS AND BACTERIAL PRESENT
To prevent infection and optimize the healing.
White blood cells to the rescue as a clean up crew.
Change from vasoconstriction to vasodilation
What is happening at the Proliferation Phase?
FILL IN THE DEFECT WITH SCAR TISSUE
Building of the new tissues called “GRANULATION”
Fragile stage of healing need to be protected from trauma/ temperature changes and chemicals.
What is happening at the Maturation Phase?
SCAR FORMATION AND INCREASING TISSUE TENSILE STRENGTH.
Increasing tensile strength so it does not open.
From type 3 colleges to type 1
Abnormal scarring happens due to?
Excessive collagen production problems?
What is Hypertrophic scar?
Are raised and thick but stay within the wound borders.
Occur in early maturation due to an overgrowth of type 3 collagen
What is Keloid scar?
Grow outside of the borders of the wound and occur in late maturation due to an overgrowth of type 1 collagen.