Tissue Architecture

Question 1

The cytoskeleton is:

Answer 1

1. Dynamic
2. Adaptable
3. Strong
4. Stable

Question 2

Are cytoskeleton filaments easy to put together and take apart?

Answer 2

Yes

Question 3

As you build up and make the cytoskeleton into bigger pieces, it becomes more _________

Answer 3

thermodynamically stable.

Question 4

Strength of intermediate filaments

Answer 4

Intermediate filaments are very strong.

The have staggered, long subunits that give it rope-like properties. Thus, they are resistant to stretching forces.

Question 5

Intermediate filaments

Answer 5

Intermediate filaments have a great tensile strength to resist mechanical forces. Thus, it forms a nuclear lamina to help strengthen the nuclear envelope

Found in the cytoplasm.

Question 6

Microtubules

Answer 6

Microtubules are responsible for ORGANIZING. Microtubules form the mitotic spindle and they are a part of the cilia and flagella.

Question 7

Microtubule structure

Answer 7

Long, still hollow tubes that rapidly assemble and disassemble. They extend from the centrosome to the cell periphery.

Question 8

What makes up a microtubule?

Answer 8

Heterodimers of alpha and beta tubulin.

This will form a protofilament, which has a +/- end. When things are added to the + end, we see faster growth.

Question 9

Protofilament

Answer 9

has a - and + end. When things are added to the + end, it grows faster.

Question 10

y-tubulin

Answer 10

y-tubulin allows for nucleation of the microtubule at the (-) end.

it is an anchor point for microtubules to grow from.

Question 11

Taxol

Answer 11

a drug that binds and stabilizes microtubules

Question 12

Colchicine

Colcemid

Answer 12

binds tubulin dimers and prevents their polymerization

Question 13

Vinblastine

Vincristine

Answer 13

binds tubulin dimers and prevents their polymerization.

Question 14

Microfilaments

Answer 14

Important for cell movement.