Tissu conjonctif : Os Flashcards

1
Q

Ostéoblaste : facteur de croissance

A

BMP7 (bone morphogenetic proteins) -> CBFa1 (core binding factor)

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2
Q

Ostéoblaste : FT

A

CBFa1 (core binding factor)

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3
Q

pH dissolution matrice osseuse (cristaux hydroxyapatite)

A

4-5

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4
Q

Enzyme de résorption de l’ostéoïde

A

Cathepsine (active en milieu acide)

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5
Q

Ostéoclaste : Facteur de fusion des monocytes

A

M-CSF

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6
Q

Ostéopétrose : gène muté (2)

A
  • Inhibition M-CSF
  • gène d’anhydrase carbonique II, ou du RANK ou RANKL.
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7
Q

Pycnodysostose : gène muté

A

Cathepsine K

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8
Q

Concertation sanguine de Ca2+

A

parathormone < 2.2 – 2.7 mmol / L < calcitonine

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