Thrombocytes, leucocytes, monocytes, hématopoïèse Flashcards

1
Q

Thrombocytes : taille

A

2 à 4 um

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2
Q

Thrombocytes : type de granule

A

Alpha
Delta à corps dense
Lambda

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3
Q

Granule Alpha : contenu

A

Eléments spécifiques des plaquettes
- Facteur plaquettaire 4
- Thromboglobulines
Réparation de VS : PDGF
Coagulation :
- Fibrogène
- Facteur V
- Facteur de von Willebrand

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4
Q

Granule Delta à corps dense : contenu

A
  • Sérotonine
  • ADP
  • Ca2+
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5
Q

Throbocytes: granules lambda

A

Enzymes lysosomales

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6
Q

Clou plaquettaire : prot produit par cel endothéliales voisines

A

Prostacycline

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7
Q

Granule azurophile : contenu

A

Myélopéroxidase Hydrolases Lysozyme

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8
Q

Neutrophile : granule spécifique : contenu

A

Gélatinase, collagénase, lactoférase

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9
Q

Neutrophile : superoxyde

A

NEDH oxydase

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10
Q

Eosinophile : récepteur IgE

A

FCepsilonR2

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11
Q

Basophile : récepteur IgE

A

FCEpsilonR1

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12
Q

Granulocytes : fréquence relative

A
  • Neutrophile : 40 à 75% : les plus fréquents
  • Eosinophile : 1 à 5% :
  • Basophile :0 à 1%
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13
Q

Mononucléaires : fréquence relative

A
  • Lymphocytes : 25 à 40%
  • Monocytes : 2 à 8%
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14
Q

Neutrophile : demie vie

A

6h à quelques jours

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15
Q

Eosinophile : demie vie

A

12 jours

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16
Q

Basophile : demie vie

A

Incertaine

17
Q

Lymphocytes : demie vie

A

Demi-vie à plusieurs années

18
Q

Neutrophile: taille

A

12 à 14 um

19
Q

Eosinophile: taille

A

12 à 17 um

20
Q

Basophile: taille

A

14 à 16 um

21
Q

Lymphocytes non actif: taille

A

5 à 8 um

22
Q

Lymphocytes actif

A

14 à 17 um

23
Q

Monocyte : taille

A

18 um

24
Q

Moelle osseuse : stroma : contenu

A
  • cellules réticulaires
  • adipocytes
  • macrophages
  • capillaires sinusoïdes
25
Q

Leucocytes : prod quotidienne

A

10 milliards

26
Q

Erythrocytes : production quotidienne

A

600 milliards

27
Q

Thrombocytes : production quotidienne

A

600 milliards

28
Q

Cellules souches : taux de reproduction

A

10^2 à 4 par année au minimum

29
Q

Mégacaryoblastes : taille

A

100 um