Thyroid tumours Flashcards
What is the most common type of thyroid cancer?
Papillary thyroid carcinoma
What questions, examinations and investigations are queried in a patient with a goitre?
History:
- previous neck irradiation?
- family history of thyroid carcinoma?
Examination:
- neck nodes
- hoarseness
Investigations:
- TSH
- US-guided aspiration
__% of women have hypothyroidism.
5%
__% of all thyroid lumps are benign.
95%
What is the normal range of TSH?
0.4-4 mU/L
In the TMN tumour classification, __ indicates minimal extrathyroidal infiltration, whereas __ indicates further invasion
T3 - local invasion
T4 - invasion outwith thyroid capsule
_________ is used as a tumour marker, used in follow up monitoring of thyroid tumours.
Thyroglobulin
-precursor of T4/3
Fine needle aspiration will confirm whether the Follicular Thyroid Carcinoma has invaded past the capsule (T/F)
False
- naw
- shows cytology only
Female, ~75yo, with auto-immune hypothyroidism, presenting with rapidly growing thyroid mass, sounds like…
thyroid lymhoma
- check histology
- treat w/ chemo
What can be used as a tumour marker in Medullary Thyroid Carcinoma?
Calcitonin
-tumour of parafollicular C-cells, which secrete calcitonin
_______ and _______ cancers are differentiated thyroid cancers. The histology looks like normal thyroid cells.
Papillary and
Follicular
______ thyroid cancer is associated with Hashimoto’s thyroiditis
Papillary
In patients with thyroid cancer, when is whole body Iodine scanning carried out?
What does the scan provide?
3-6 months post op in patients who have undergone thryroidectomy
- detects spread
- Confirms whether Radioactive Iodine treatment should be used
Why can Thyroglobulin be used as a sensitive differentiated tumour marker?
It is produced by thyroid cells and differentiated tumours.
-patients treated with thyroidectomy +/- radioactive iodine should produce none
