Thyroid + Triangles of Neck + Airway Obstruction Flashcards
What are the boundaries of the anterior triangle
Midline of neck to anterior border of SCM
What are the contents of the anterior triangle
CCA - internal + external Internal jugular vein Facial vein and artery Vagus nerve Hypoglossal nerve Glossopharyngeal nerve Laryngeal nerve nerve Submandibular and submental node
What are the boundaries of posterior triangle of the neck
External jugular vein Cervical neck plexus Lymph nodes Occipital artery Accesory nerves
Anatomy of thyroid gland
Attached to individual framework so moves up and down when you swallow
2 lobes
Joined by isthmus
What is a thyroglossal cyst
Dilatation of thyroglossal duct remnant
Thyroid formed when foramen caecum from tongue drops down
If connection still exist then cyst forms
What are the features of a thyroglossal cyst and how do you Dx
Lump in midline of neck - mobile, non-tender, soft and fluctuant
Grows with age
Moves upwards on tongue protrusion as connected to foramen caecum
Can become infection and discharge with risk of discharging sinus formation
How do you Dx and Rx thyroglossal cyst
USS prior to ensure functioning thyroid tissue as would leave patient hypothyroid
+- FNAC
May reoccur
Need to remove hyoid bone first for surgery
Only Rx if complication e.g. infection
What are complications of thyroid surgery
Recurrent laryngeal damage
Bleeding
Hypocalcaemia due to damage to parathyroid
Who are thyroid lumps common in
Middle age = 10% malignant
If in the young then 50% malignant
What can a solitary nodule in the thyroid be
Cyst Adenoma Carcinoma Lymphoma Prominent nodule in multi-nodular goitre
What is 1st line investigation
USS to risk stratify and look for malignant cervical LN
+- FNAC
FNAC if suspicious
- Can Dx papillary
- Cannot distinguish between follicular adenoma and carcinoma
How do you DX thyroid cancer
Thyroid function test
MRI
CT but try to avoid due to radiation
What does results of USS / FNAC determine
If nothing = reassure and discharge
If suspicious need to remove thyroid for histological Dx as FNAC can’t differentiate between adenoma and carcinoma
How do you grade result
1 - non diagnostic 2 - normal 3 - borderline 4 - concerning, most likely cancer 5 - cancer
Concerning features
- Solid hypochenic
- Microcalcification
- Irregular
- LN
What are types of thyroid cancer in order of commonest
Papillary - most common
- <40F
- Lymph mets to cervical LN
- RF = RT
Follicular
- Tend to be more middle age
- RF = iodine deficiency
- Blood mets - brain, bone, lung liver
Medullary
- Originate parafollicular C cells
- Middle age
- MEN 2A or 2B
- Can do genetic screen for RET mutation and check urine metanephrine prior to surgery for pheochromocytoma prior to any surgery
Anoplastic
- Aggressive - rapidly enlarging neck mass over 2-3 months
- Elderly
- Local spread
- Dx requires biopsy and Rx most likely palliative
Lymphoma
- Diffuse large B cell
- RF = hashimoto
- Dx = biopsy
- Rx = chemo / RT as per lymphoma oncology team
What are the symptoms of thyroid cancer
Painless lump in front of the neck Swollen glands - cerivcla Patient usually euthyroid Unexplained hoarseness Sore throat Dysphagia
What are RF for cancer
Women Thyroiditis Goitre FH Radiation exposure Obesity Acromegaly FAP
What is the investigation process + treatment
USS to look at size, LN and mets
Non contrast CT / MRI may be needed if neck nodes
Cold nodules on schintogrpahy
Surgery
- Thyroid lobectomy
- Total thyroidectomy - if >1cm or high risk follicular
- Neck dissection if established mets in LN
RAI
- Used in papillary and follicular
- No use in medullary as tumour from neuroendocrine cells NOT follicular
Other
External RT and chemo
Replacement thyroxine as suppress gland + prevent recurrence +- calcium may be needed after
Follow up
- Thyroglobulin at 6 weeks (tumour marker)
- USS +-FNAC
What is a goitre
Swelling in the neck due to enlarged thyroid
Diffuse = whole gland
What are types of goitre
Simple colloid
Multi-nodular
Neoplastic
Inflammatory
What is a colloid goitre
Benign non-cancerous enlargement of thyroid gland
What causes
Iodine deficiency
Puberty
Pregnancy
Lactation
What can it cause / never cause
Compressive neck symptoms
No bruit
No hormonal abnormalities