Thyroid Physiology Flashcards

1
Q

List the main thyroid hormones

A

Thyroxine (T4)
Triiodothyronine (T3)
Calcitonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What chemical is the main “fuel source” of the thyroid?

A

Iodine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What happens to iodine once it is taken up by the follicle cells of the thyroid?

A

Combines with tyrosine residues on thyroglobulin to form MIT or DIT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Outline the composition of T3

A

MIT + DIT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Outline the composition of T4

A

DIT + DIT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

T3 is the more abundant thyroid hormone. True/False?

A

False

T4 makes up 90% of thyroid hormones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Is T3 or T4 more biologically active?

A

T3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

T4 is converted to T3 by liver/kidney. True/False?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

The unbound form of thyroid hormone is biologically inactive. True/False?

A

False

Unbound is active!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the 2 main types of cell found in the thyroid?

A

Follicular cells

Parafollicular C cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is stored in the colloid of the thyroid?

A

Thyroglobulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What do follicular cells secrete?

A

Thyroglobulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

T3 and T4 are hydrophobic. True/False?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What do parafollicular cells secrete?

A

Calcitonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Where is the thyroid located?

A

C5/T1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly