Neonatal diabetes Flashcards
1
Q
What are the two types of Neonatal diabetes
A
Transient
Permanent
2
Q
Transient Neonatal diabetes
A
Occurs very rapidly after birth, but resolves within 12 weeks.
Disease re-occurs in adolescence
3
Q
Permanent Neonatal diabetes
A
Appears within first 6 weeks
4
Q
In neonatal diabetes with a Kir 6.2 mutation what is the treatment of choice?
A
Sulphonylureas
- Tolbutamide - Glibenclamide
5
Q
What is the defining point of neonatal diabetes that can help point towards the diagnosis?
A
A neonate requiring insulin injection within 2 weeks of birth.
Insulin is withdrawn over time to be replaced by SU’s