Thyroid/Osteoporosis (lec 26)

Question 1

Thyroid regulated by?

Answer 1

TSH and iodine

Question 2

Thyroid effects on body?

Answer 2

↑ BMR

Growth/maturation

Question 3

Hypothyroid caused by?

Most common cause?

Answer 3

↓ TH from any level of HPT

thyroid gland failure (see high TSH)

Question 4

Hypothyroid signs/sxs?

Answer 4

Slow metabolic rate:
weight gain,
cold sensitive,
fatigue,
slow speech/memory,
thick/dry skin,
puffy hand/face,
goiter

Question 5

Hyperthyroid caused by?

Answer 5

Grave’s:
TSH-receptor antibodies

Toxic Nodular Goiter:
Adenoma of thyroid

Question 6

Hyperthyroid signs/sxs?

Answer 6

Fast metabolism:
tachy,
fatigue,
hot/sweaty,
tremors,
insomnia,
N/V/D,
weight loss

Question 7

Bone remodeling caused by?

Answer 7

Osteoclasts breakdown/resorb bone

Osteoblasts form/deposit bone

Question 8

Bone remodeling regulated by?

Answer 8

Resorption

Question 9

RANKL is?

Answer 9

receptor activator of nuclear factor kappa-beta ligand ->
stimulate osteoclasts (breakdown/resorb)