Thyroid Nodules Flashcards

1
Q

Thyroid Nodules epidemiology and kinds

A

Ninety-five percent are benign (adenoma, colloid nodule, cyst).
Rarely asoc. w clinically apparent hyperfunctioning
or hypofunctioning.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Thyroid Nodules, management if found

A

first: t4 and TSH level

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Thyroid Nodules dx test. when to aspirate?

A

if >1.5 cm + normal thyroid function (T4/TSH) or “elevated”.= must be biopsied with a fine-needle aspirate

this is a high risk.

no need of US or RIUS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

If biopsy shows indeterminant for follicular adenoma, what to do?

A

Surgical removal (excisional biopsy).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

If biopsy shows medullary carcinoma.

A

Calcitonin

levels are useful to get

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what pt are at higher risk to develope nodules?

A

Radiation exposed. Like hodking limphoma survivros
Hx of Cancer , personal o fam
Hoarseness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

at what agre range are pt at higher risk to develope nodules?

A

Age <20 >60

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

if its non painfull, very less likely to be ca T/F

A

T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

US Malignany signs

A

Solid hypoechogenic.
Size >2cm
microcalcification, irregular borders

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what to do if hyper funcioning nodule?

A

trear hyperthyroidism: start with Beta blockers +
Antithyroid drugs to achieve euthyroidism

then go with Definitive treatment options:
Hemithyroidectomy
Radioactive iodine ablation (RAIA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What does it mean a RAIU with hot or cold results

A

hot=hyperfunctioning

cold= nonfunctioning = CA risk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what to do if RAIU = cold

A

US & FNA biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What to do if TSH is low + nodule

A

do RAIU, and next step would be according cold/hot result

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What to do if TSH is high + nodule

A

US. if >1cm FNA

if <1cm US 6-12 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

If biopsy shows no CA

A

US 6-12 month

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what kind of CA can show the thyroid biopsy

A

Papillary 80%
Follicular
Medullaty
Anaplastic

17
Q

Papillary CA bx shows:

And how would you treat this kind of cancer?

A

biopsy shows orphan Annie-eye nuclei. psammoma bodies (round collection of calcium)

QX !

18
Q

Follicular CA patho and tx

A

FNA says is normal thyroid, spreads hematoneiusly

tx Radio active I2 ablation. would be like a systemic chemo

19
Q

Medullary CA patho and tx

A

by c-cells, calcitonin producers. lowers Ca
Can be part of MEN, along with pheochromocitoma.
RET oncogene

20
Q

Anaplastic patho

A

FATAL, elderly. locally invasive.