Thyroid | Head + Neck Cancers Flashcards

1
Q

Risk factors of head + neck cancers

A
  • smoking
  • alcohol
  • beta nut chewing (oral cancer)
  • dental hygiene (oral cancer)
  • viruses (e.g. HPV 16 for oropharynx)
  • erythroplakia
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2
Q

Risks of thyroid cancer

A
  • radiation exposure
  • family history
  • female
  • young + old people’s lumps are more likely to be malignant
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3
Q

Supportive Managment of H+N cancers

A
  • swallowing
  • feeding
  • voice rehab
  • pain
  • supportive care
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4
Q

Presentation of lip/oral cavity cancer

A
  • lump
  • pain > can refer to ear
  • fixation of tongue
  • dysphagia
  • odynophagia
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5
Q

What is odynophagia?

A

Pain on swallowing

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6
Q

Investigations of lip/oral cavity cancer

A
  • biopsy
  • CT +/- MRI (including chest)
  • PET
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7
Q

Treatment of lip/oral cavity treatment

A
  • small tumour excise + repair
  • radiotherapy
  • extensive surgery for larger tumours that don’t respond to radiotherapy (hemiglossectomy/total glossectomy)
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8
Q

Presentation of pharynx cancer

A
  • often asymptotic > present with advanced disease
  • lump
  • pain
  • referred otalgia
  • dysphagia
  • odynophagia
  • weight loss
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9
Q

Investigation of pharynx cancer

A
  • biopsy
  • CT +/- MRI (including chest)
  • PET
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10
Q

Treatment of pharynx cancer

A
  • small tumour excise + repair
  • radiotherapy
  • extensive surgery for larger tumours that don’t respond to radiotherapy
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11
Q

Presentation of larynx cancer

A
  • dyphnoia (main feature) - hoarse voice
  • dysphagia
  • referred otalgia
  • globus
  • neck lump
  • weight loss
  • cacexia
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12
Q

What is dyphonia?

A

Voice change

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13
Q

What is globus?

A

Persistent or intermittent non painful sensation of lump in throat

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14
Q

What is cacexia?

A

Weakening + wasting of body due to severe chronic illness

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15
Q

Investigations of larynx cancer

A
  • CT (including chest)
  • PET
  • biopsy
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16
Q

Treatment of larynx cancer

A
  • small tumours: laser resection or radiotherapy
  • medium sized tumours: radiotherapy +/- chemotherapy
  • large tumours: that do not respond to radiotherapy may need laryngectomy
17
Q

Presentation of thyroid cancer

A
  • lump in thyroid
  • neck nodal metastasis
  • dysphagia
  • feeling like being strangled
  • dysphonia - hoarseness of voice
18
Q

Investigations of thyroid cancer

A

Triple assessment
- full history + exam
- ultrasound
- needle testing of suspicious lumps as fine needle aspiration cytology

19
Q

Head and neck cancers red flags

A
  • persistent hoarseness of voice
  • unexplained neck lump
  • mass on lip or oral cavity
  • erythroplakia or erythroleukoplakia
20
Q

What is erythroplakia?

A

Red patches on tongue + oral cavity

21
Q

What is erythroleukoplakia

A

Combination of leukoplakia + erythroplakia
White + red patches on tongue + oral cavity

22
Q

What is the most common type of thyroid cancer?

A

Papillary adenocarcinoma
Then follicular adenocarcinoma

23
Q

Treatment of thyroid cancer

A
  • surgery (thyroidectomy)
  • radio-iodine therapy: after total thyroidectomy to kill residual malignant cells
  • radiotherapy
24
Q

Types of thyroid cancer

A

Papillary adenocarcinoma
Follicular adenocarcinoma
Medullary carcinoma
Anaplastic carcinoma
(Lymphoma)

25
Q

What do patients who have a total thyroidectomy need post op?

A

Lifelong thyroxine replacement

26
Q

What is the most common type of cancer of the head and neck?

A

Squamous cell carcinoma