Thyroid Gland Disorders Flashcards
Thyroid gland secretes the following hormones
T3
T4
Thyrocalcitonin
T3 (Triidothyronine) Function
Metabolism and Growth
T4 (Thyroxine, tetraiodothyronine)
Catabolism and Body Heat Production
regulates serum Ca++ levels
bring down the blood Ca++ level
Thyrocalcitonin
Increase T3 = Increase metabolic rate
Increase T4 = Increase body heat production
Increase Thyrocalcitonin = Decrease calcium
Hyperthyroidism (Thyrotoxicosis)
Hyperthyroidism Cause: most common cause
Grave’s Disease
Hyperthyroidism Cause: autoimmune disorder due to the production of an antibody/immunoglobulin TSI (thyroid stimulating immunoglobulin) that has the same effect as TSH…this stimulates the body to produce high amounts of thyroid hormones (genetic)
Grave’s Disease
Hyperthyroidism Cause: not autoimmune…growths of nodular goiters that are independently functioning to cause hypersecretion of thyroid hormones
Toxic Nodular Goiter
Hyperthyroidism Cause: inflammation of the thyroid gland and this can cause T3 and T4 leak into the body
Thyroiditis
Hyperthyroidism Cause: Protruding eyeballs, goiter, pretibial myxedema: waxy orange peel appearance of the skin found in the feet and legs
Grave’s Disease
Hyperthyroidism Cause: won’t see ophthalmic signs like the protruding eye balls but the classic signs and symptoms of hyperthyroidism
Toxic Nodular Goiter
Hyperthyroidism CM: HR?, BP?
Tacycardia, Hypertension
Hyperthyroidism CM: ? Appetite, ? Loss
Voracious
Weight
Hyperthyroidism CM: Frequent ?, ? Intolerance
Sweating (Diaphoresis)
Heat
Hyperthyroidism CM: absence of ? in F, ? hair, ? nails
Menstruation (Amenorrhea)
Fine Silky
Pliable
Hyperthyroidism CM: Mood Changes?, Fine ?
Irritability, Restlessness, Nervousness
Tremors
Hyperthyroidism Interventions: Provide a ? and ? environment
Cool, Quiet
Hyperthyroidism Interventions: Provide adequate ? Administer ? as prescribed
Rest
Sedatives
Hyperthyroidism CM: Due to accumulation of fluids, mucopolysaccharides at the fat-pads behind the eyeballs, it can lead to corneal ulceration
Exopthalmos
Hyperthyroidism CM: Long and deep palpebral fissure is still evident when one looks down
Von Graefe’s Sign (Lid Lag)
Hyperthyroidism CM: Forehead remains smooth when one looks up
Jeffrey’s Sign
Hyperthyroidism CM: Bright-eyed stare, infrequent blinking
Dalyrimple’s Sign (Thyroid Sign)
Hyperthyroidism CM: Warm, flushed sweaty skin
Thickened hyper-pigmented skin at the pretibial area
Dermopathy
Hyperthyroidism Interventions: Diet ?
High Calorie and CHON
Vitamin and Mineral Supplements
Fluid Intake (If there’s diarrhea)
Hyperthyroidism Interventions: Avoid Stimulants like ?
Coffee, Tea, and Nicotine
Hyperthyroidism Interventions: Obtain ? daily
Weight (Same Time, Clothes, Weighing Scale)
Hyperthyroidism Interventions: Protect the eyes by ?
Using artificial tears at regular intervals
Wearing dark sunglasses
Taping eyelids at night (if necessary)
Hyperthyroidism Interventions: Prepare the client for ? therapy, → destroys thyroid cells
Radioactive Iodine
Hyperthyroidism Interventions: Prepare the client for ?if prescribed
Subtotal Thyroidectomy
Hyperthyroidism Pharmacotherapy: ß-blockers
Propanolol
Hyperthyroidism Pharmacotherapy: These drugs are given to control tachycardia and HPN
Ca+ Channel Blockers
Hyperthyroidism Pharmacotherapy: Are given to inhibit release of thyroid hormone
Iodides: Lugols Solution (SSKI Saturated Solution of Potassium Iodide)
Hyperthyroidism Pharmacotherapy: Iodides: Lugol’s solution shoul be mix with ? with ? or glass of water to improve its palatability
Fruit Juice
Ice
Hyperthyroidism Pharmacotherapy: Iodides: Lugol’s Solution - Provide drinking straw to prevent permanent ?
staining of teeth
Hyperthyroidism Pharmacotherapy: Iodides: Lugol’s Solution Side Effects?
Allergic Reaction, Increased Salivation, Colds
Hyperthyroidism Pharmacotherapy: These are given to inhibit synthesis of thyroid hormones
Thioamides
Hyperthyroidism Pharmacotherapy: Thioamides
PTU (Propylthiouracil)
Tapazole (Methimazole)
Hyperthyroidism Pharmacotherapy: Side effects of PTU
Agranulocytosis
Neutropenia
Hyperthyroidism Pharmacotherapy: ? must be avoided because it can displace the T3/T4 from the albumin in the plasma causing increased manifestations
Aspirin
Hyperthyroidism Pharmacotherapy: inhibit the action of thyroid hormones
Dexamethasone
Hyperthyroidism Pharmacotherapy: NOT recommended in pregnant women because of
potential teratogenic effects. Pregnancy should be
delayed for ? months after therapy
Radiation Therapy (Iodine)
6 mos
Hyperthyroidism Subtotal Thyroidectomy: Usually about ? of the gland is removed
5/6
Hyperthyroidism Subtotal Thyroidectomy: Position
Semi-fowler’s with head, neck, shoulders erect
Hyperthyroidism Subtotal Thyroidectomy: Prevent Hemorrhage
Ice collar over the neck
Hyperthyroidism Subtotal Thyroidectomy: Keep ? set available for the first ? post-op
Tracheostomy
48 hrs
Hyperthyroidism Subtotal Thyroidectomy: Ask the patient to ? (to assess for recurrent laryngeal nerve damage)
Speak every hour
Hyperthyroidism Subtotal Thyroidectomy: Keep ? readily available – ? occurs if hypocalcemia is present. This may be secondary to the accidental removal of the parathyroid gland
Ca+ Gluconate
Tetany
Hyperthyroidism Subtotal Thyroidectomy: Monitor Body Temperature - ? is an initial sign of thyroid crisis
Hyperthermia
Hyperthyroidism Subtotal Thyroidectomy: ? exercises of the neck ? days after discharge
ROM
3-4 days
Sudden, life-threatening exacerbation of hyperthyroidism/thyrotoxicosis
Thyroid Crisis/Storm
Thyroid Crisis Causes
Stress, Infection, Unprepared Thyroid Surgery
Thyroid Crisis Causes: taking medications that increase thyroid hormones
Salicylates (ASA)
Thyroid Crisis CM: Initial sign
Elevated Temperature (Fever)
Thyroid Crisis CM: HR, BP, RR
Tachycardia
Hypertension
Tachypnea
Thyroid Crisis CM: Neurologic State and Conciousness
Restlessness, Apprehension, Tremors, Delirium, Psychotic State, Coma
Thyroid Crisis Interventions: Monitor?
BP, HR, RR, Temperature, I and O
Neurologic Status
Thyroid Crisis Interventions: Keep environment ? and ? cool (? and ? as prescribed)
Quiet, Cool
Cooling Blankets, Sedatives
Thyroid Crisis CM: No foods containing ? (seafood…seaweed, dairy, eggs)
Iodine
Thyroid Crisis Interventions: Administer increasing doses of oral ?- (? mg q ? hrs) as ordered, following a loading dose of ? mg. p.o as ordered
PTU, 200-300mg, 6hrs
800-1,200mg
Thyroid Crisis Interventions: Administer ? to help inhibit the release of thyroid hormone
Administer ? to control hypertension and tachycardia
Dexamethasone
Propranolol
Thyroid Crisis Interventions: Implement measures to lower fever
- cooling devices
- cold baths
- ? (avoid ?)
Acetaminophen
Aspirin
hyposecretion of thyroid hormones
Hypothyroidism
characterized by a decreased rate of body
metabolism
Hypothyroidism
thyroid gland cannot produce the necessary amount of hormones
Primary Hypothyroidism
thyroid is not being stimulated by the pituitary gland to produce hormones
Secondary Hypothyroidism
Decrease T3 = Decrease metabolic rate
Decrease T4 = Decrease body heat production
Decrease Thyrocalcitonin = Increase calcium
Hypothyroidism
Hypothyroidism Causes: an autoimmune disorder in
which your immune system inappropriately attacks your thyroid gland causing an inflammation
Hashimoto’s Disease or Chronic Lymphocytic Thyroiditis
Hypothyroidism Causes:
after surgery ?
after radiation therapy ?
? drugs
Thyroidectomy
Radioactive Iodine
Antithyroid
Hypothyroidism CM: ? Hair, Loss of ? Hair, ? Face
Dry, Coarse Hair
Eyebrow
Puffy
Hypothyroidism CM: Swelling of the skin (eyes and face) that gives it a waxy appearance
Dull, ? , mask-like ?
Myxedema
Expressionless, Face
Hypothyroidism CM: ? Skin, ? Nails
Dry
Brittle
Hypothyroidism CM: Weight Gain? , ? Pain
Hyperlipidemia & Atherosceloris
Muscle
Hypothyroidism CM:
Slow ?
? voice
? tongue
Slowed
Husky, Hoarse
Enlarged
Hypothyroidism CM: Irregular menstruation
Menorrhagia, Amenorrhea
Hypothyroidism CM: GI Disturbance
Constipation
Anorexia
Hypothyroidism CM: ? physical, mental reactions, ?
Extremely tired and ?
Slowed, Apathy
Fatigue
Hypothyroidism CM: ? intolerance, ? temperature
HR ?
Cold, Subnormal
Bradycardia
Hypothyroidism Intervention: Monitor ?
VS (HR, BP, EKG)
Weight daily
Hypothyroidism Intervention: Diet, Encourage ?
Low Calorie, High Fiber
Fluids
Hypothyroidism Pharmacotherapy: Thyroid hormonal replacement
Proloid (Thyroglobulin)
Synthroid (Levothyroxin)
Dessicated Thyroid Extract
Cytomel (Liothyronine)
Hypothyroidism Pharmacotherapy: Thyroid hormonal replacement - Most Common
Synthroid (Levothyroxine)
Hypothyroidism Pharmacotherapy: Thyroid hormonal replacement - Before administration, the nurse should monitor ? & ?
BP, PR
Hypothyroidism Pharmacotherapy: Thyroid hormonal replacement - Start with ? and gradually ?
Low dose
Increase
Hypothyroidism Pharmacotherapy: Thyroid hormonal replacement - Don’t ? taking (takes a while for signs and symptoms to improve)
abruptly stop
Hypothyroidism Pharmacotherapy: Thyroid hormonal replacement - Take at the ? every day in the morning without ?
Same time
Food
Hypothyroidism Pharmacotherapy: Thyroid hormonal replacement - Don’t take within ? of multivitamins, GI medications like Carafate, aluminum hydroxide, simethicone….decreases absorption of thyroid medication
4 hours
Hypothyroidism Pharmacotherapy: Note patients with hypothyroidism are sensitive to narcotics like ? (avoid dilaudid, morphine, fentanyl) and other ? (could lead to myxedema coma). Instead use alternatives for pain as prescribed like non-narcotics ?
Opoids, Sedatives
Tylenol, Ibuprofen
Extreme, severe stage of hypothyroidism, in which the
client is hypothermic and unconscious
Myxedema Coma
Myxedema Coma CM: ? (not just cold intolerance)
Hypothermia
Myxedema Coma CM: swelling of tissues that have a waxy appearance or orange peel texture which will be located on the eyes and face
Myxedema
Myxedema Coma CM: ? heart rate and ? blood pressure
? failure (most likely will need mechanical ventilation)
Slow, Low
Respiratory
Myxedema Coma CM: due to the increased antidiuretic hormone which causes the body to conserve water & decreased glomerular filtration rate because there is decreased blood flow to the kidneys
Hyponatremia
Myxedema Coma CM: due to the reduced metabolic rate hence decreased gluconeogenesis
Hypoglycemia
Myxedema Coma CM: Very ? may progress to a coma
Confused/Drowsy