Thyroid gland

Question 1

most active thyroid hormonal activity

Answer 1

T3 (triiodothyronine)/ 3,5,3’triiodothyronine

Question 2

To diagnose t3 thyrotoxicosis

Answer 2

T3

Question 3

Better indicator for hyperthyroidism

recognize recurrence of hyperthyroidism

Answer 3

T3

Question 4

confirming diagnosis for hyperthyroidism with no or minimally elevated t4

Answer 4

T3

Question 5

first abnormality seen in cases of hyperthyroidism

Answer 5

increase in plasma levels of T3

Question 6

first abnormality seen in cases of hyperthyroidism

Answer 6

increase t3 in plasma levels

Question 7

Principal secretory product

Answer 7

T4

Question 8

major fraction of organic iodine in the circulation

Answer 8

T4

Question 9

good indicator of thyroid secretory rate

Answer 9

T4

Question 10

elevated thyroxine causes inhibition to

Answer 10

TSH secretions

Question 11

transports majority of T3
transports 70 to 75% of total T4

Answer 11

Thyroxine-binding globulin (TBG)

Question 12

transports 15-20% of total t4

Answer 12

Thyroxine-binding prealbumin (transthyretin)

Question 13

Transports T3 and 10% of T4

Answer 13

Thyroxine binding albumin

Question 14

invoved in tissue destructive process (hashimoto’s disease)

Answer 14

Thyroperoxidase (TPO)

Question 15

TSH receptor

Answer 15

involved in Grave’s disease

Question 16

measures relationship between TRH and TSH secretions

differentiate euthyroid and hyperthyroid in patients who had undetectable TSH levels

detects thyroid resistance syndromes

borderline cases of grave’s disease

Answer 16

TRH stimulation test (Thyrotropin Releasing hormone)

Question 17

Most important thyroid function test

Best method for detecting clinically significant thyroid dysfunction

most sensitive assay for primary thyroid disorders

Monitor and adjust thyroid hormone therapy

Answer 17

TSH test

Question 18

measure trap iodine

establish cause of hyperthyroidism

high uptake indicated metabolically active gland

Answer 18

Radioactive uptake (RAIU)

Question 19

high uptake + TSH deficency =

Answer 19

autonomous thyroid activity

Question 20

normally used postoperative marker for thyroid cancer

Answer 20

Thyroglobulin (Tg) assay

Question 21

monitors recurrence/metastatic of thyroid cancer

Answer 21

Thyroglobulin assay

Question 22

differentiates subacute thyroiditis and thyrotoxicosis

Answer 22

Thyroglobulin assay

Question 23

removal of one iodine from the inner ring of T4

Answer 23

Reverse T3

Question 24

endproduct of T4 metabolism

Answer 24

Reverse T3

Question 25

3rd major circulating thyroid hormone

Answer 25

Reverse T3

Question 26

identifies euthyroid sick syndrome

Answer 26

Reverse T3: elevated

Question 27

assess borderline or conflicting laboratory result

Answer 27

Reverse T3

Question 28

assess level of free t4 in blood

Answer 28

Free thyroxine index

Question 29

equilibrium relationship of bound t4 and Ft4

Answer 29

Free thyroxine index

Question 30

correcting euthyroid indivs

Answer 30

Free thyroxine index

Question 31

test is used to differentiate drug induced TSH elevation and hypothyroidism;

Answer 31

FT4

Question 32

measures available binding site of thyroxine binding proteins

Answer 32

T3 uptake

Question 33

used to confirm results of FT3 and FT4 abnormalities

Answer 33

Thyroxine binding globulin

Question 34

most accurate tool for evaluation of thyroid nodules

Answer 34

fine needle aspiration

Question 35

detecs pesence of residual or recurrent disease

Answer 35

Recomobinant human TSH

Question 36

tumor marker for detecting thyroid metastasis

measured 6 months after surgery

Answer 36

Serum calcitonin

Question 37

diagnosis of MTC

Answer 37

Pentagastrin stimulation test