Thyroid dysfunction Flashcards
1
Q
- Identify the major symptoms and signs of hyperthyroidism.
A
Nervousness 84% Weight Loss 51% Increased Appetite 57% Decreased Appetite 4% Fatigue 84% Tremor 84% Heat Intolerance 92%
2
Q
- List the disorders leading to hyperthyroidism.
A
High Uptake Hyperthyroidism
Thyrotropin receptor antibody -Graves’ disease Thyroid autonomy -Toxic adenoma -Toxic multinodular goiter (MNG)
Low Uptake “Hyperthyroidism
-Subacute thyroiditis
—–Granulomatous thyroiditis (viral); de Quervain’s
-Chronic lymphocytic thyroiditis (Hashimoto’s)
—–Postpartum thyroiditis
Ectopic thyrotoxicosis
-Factitious
3
Q
- Recognize the major symptoms and signs of hypothyroidism.
A
Mental Slowness 68% Weight Gain 58% Decreased Appetite 50% Fatigue 83% Muscle Cramps 55% Cold Intolerance 65%
4
Q
- Name the conditions leading to hypothyroidism.
A
Primary Hypothyroidism
Chronic autoimmune (Hashimoto’s) thyroiditis
Transient hypothyroidism
- Silent or postpartum thyroiditis
- Subacute or granulomatous thyroiditis
Iatrogenic
- Thyroid surgery/thyroidectomy
- Radioactive iodine
Central Hypothyroidism (2˚/3˚) -Pituitary tumor
5
Q
- Interpret the different tests used to evaluate thyroid function.
A
TSH
- increased means low T3 or TSH secreting tumor
- decreased means high T3, or pituitary trauma
Radioactive Iodide uptake
- If TSH is suppressed, there should be no uptake of iodine.
- normal/ elevated iodine uptake in the setting of a low TSH is abnormal and indicates autonomous production of thyroid hormone = true hyperthyroid state.
- If uptake is low (appropriately so, in the setting of a low TSH), then thyroid hormone excess is due to high release of preformed thyroid hormone.
Thyroid scan – pattern gives info
on etiology of high uptake
(Graves’ vs. hot nodule vs.
multinodular goiter)
6
Q
Whats The single best test to screen for thyroid dysfunction
A
TSH level
7
Q
what is thyrotoxicosis
A
Thyrotoxicosis
high levels of circulating thyroid hormone
