Thyroid Drugs and Effects

Question 1

Iodine

Answer 1

Inhibits thyroid function

Increase level of TSH

Question 2

Lithium

Answer 2

Inhibits thyroid function

Increased level of TSH

Question 3

Glucocorticoid

Answer 3

Inhibition of T4 to T3 conversion

Decreased level of TSH

Question 4

Ipodate

Answer 4

Inhibition of T4 to T3 conversion

Question 5

Propanolol

Answer 5

Inhibition of T4 to T3 conversion

Question 6

Amiodarone

Answer 6

Inhibition of T4 to T3 conversion
–Converts to iodine and is transferred across placenta. Fetus cannot downregulate peroxidase activity until late gestation so they oranification of iodine excess. –» in utero and neonatal hypothyroidism

Question 7

PTU

Answer 7

Inhibition of T4 to T3 conversion

Question 8

Dopamine antagonist

Answer 8

Increased level of TSH

Question 9

Phenytoin

Answer 9

Inhibition of T4 and T3 binding to binding proteins

Question 10

Salicylates

Answer 10

Inhibition of T4 and T3 binding to binding proteins

Question 11

Sulfonylureas

Answer 11

Inhibition of T4 and T3 binding to binding proteins

Question 12

Ferrous sulfate

Answer 12

Inhibits absorption in GI tract

Question 13

Sucralfate

Answer 13

Inhibits absorption in GI tract

Question 14

Aluminum Hydroxide

Answer 14

Inhibits absorption in GI tract