Random Information

Question 1

Management of Thyroid Storm

Answer 1

1) Load with PTU 600 mg PO, then 300mgs q 6hr
2) Potassium Iodide 5gtt q8hrs
3) Dexamethasone 2mgs q 6hrs
4) Propanolol 20-40 mgs bid

Question 2

Intubation requirements

Answer 2

1) Respiratory rate >35
2) PaO2 >40 mmHg
4) A-a gradiaent >450
5) Apnea
6) Respiratory muscle fatigue
7) inability to protect airway
8) hemodynamic instability

Question 3

Asthma intubation requirements

Answer 3

Any of the following

1) Inability to maintain pO2 > 60 mmhg
2) Inability to maintain pCO2 <40 mmHg
3) Maternal exhaustion
4) Worsening acidosis despite
5) bronchodilator therapy
6) Altered mental status

Question 4

Asthma attack management

Answer 4

If respiratory distress–> admit
If Peak flow is < 50% then mange with Beta agoinsts (high dose) and steroid systemic–> repeat assesment If not above 70% PEF–> admit,

Question 5

What you need to calculate the post hoc power analysis for this study

Answer 5

For a given primary outcome:

1) Endpoint means +/- Standard error
2) Number of subjects in each group
3) Desired alpha error

Question 6

Need to caclulate Sample size-Assuming 2 independent groups with continuous primary outcome (EBL example)

Answer 6

1) Primary mean endpoint overall (i.e. Blood loss from hysterectomy
2) Desired clinical reduction over the mean
3) Desired alpha error
4) Desired power of study
5) Enrollment ratio