Thyroid Drugs

Question 0

Radioactive Iodine

Answer 0

Radioactive Iodine (131): is given which emits gamma rays in the thyroid tissue and destroys thyroid cells.

Question 1

High iodide administration

Answer 1

High Iodide concentrations: cause acute inhibition of iodide trap and hormone release.

Question 2

propylthiouracil, methimazole, and carbimazol

Answer 2

Thioamides (thioureylenes): antithyroid drugs containing tiocarbamide group. Include propylthiouracil, methimazole, and carbimazol. Sometimes used to treat graves disease. They inhibt thyroid peroxidase, but effects are not seen for a couple of weeks because of the unique storage of iodide in the colloids of the thyroid. Usually high concentrations of iodide are given to inhibit the release of thyroid hormone while the drug exerts its effects.

Question 3

Proterelin

Answer 3

Synthetic derivative of TRH which is used to see if TRH can stimulate TSH effectively.