Thyroid Drugs

Question 1

Sodium levothyroxine (Synthroid, Levothyroid)

Answer 1

Synthetic T4 for hypothyroidism

Question 2

Thyroid USP (from pig/sheep)

Answer 2

• dried, defatted thyroids

- unpredictable strength

Question 3

Sodium liothyronine

Answer 3

• synthetic T3 for myxedema coma, given by IV

Question 4

Liotrix (Euthroid)

Answer 4

4:1 ratio of T4:T3 for hypothyroidism

Question 5

Thioamides

Answer 5

• propylthiouracil (PTU), methimazole, carbimazole
• thyroid peroxidase inhibitor
• methimazole crosses placenta, causes MR

Question 6

Propanolol, atenolol

Answer 6

• beta blockers for thyroid storm

Question 7

Lugol’s solution

Answer 7

• 10% KI, 5% I2, diminishes vasculature of thyroid

Question 8

Radioactive 131I

Answer 8

• radioactive iodide destroying thyroid (first choice for hyperthyroidism)
• never use in pregnancy

Question 9

1, 25(OH)2D3 + Ca2+

Answer 9

• hypoparathyroidism

Question 10

Bisphosphonates

Answer 10

• alendronate

- for Paget’s disease or osteoporosis

Question 11

Teriparatide

Answer 11

• active portion of PTH, for postmenopausal osteoporosis

- if bisphosphonates are no longer tolerated