Pituitary Drugs

Question 1

Somatropin

Answer 1

• synthetic GH analog for hypopituitary dwarfism

Side Effects: carpal tunnel syndrome

Question 2

Sermorelin

Answer 2

• synthetic GHRH analog, for hypopituitary dwarfism

Question 3

Mecasermin

Answer 3

• recombinant IGF-1 combined with IGF BP-3, for Laron syndrome

Question 4

Pegvisomant

Answer 4

GH antagonist, for acromegaly

Side Effects: injection site reactions, nausea, diarrhea, chest pain, flu syndrome

Question 5

Bromocriptine

Answer 5

• dopamine agonist, for hypersecretion of GH or hyperprolactinemia

Question 6

Octreotide

Answer 6

• synthetic analog of somatostatin, for hypersecretion of GH; also inhibits VIP secretion for pancreatic cholera
  Side effects: diarrhea, nausea, abdominal pain