THYROID DISORDERS Flashcards

1
Q

function of thyroid hormones

A

control the rate of glucose which is used by the cell
brain development
growth

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2
Q

other name for T3

A

triiodothyronine

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3
Q

other name for T4

A

tetraiodothyronine

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4
Q

this is an important part of thyroid hormone that is stored in the thyroid gland

A

iodine

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5
Q

how does goiter happens?

A

thyroid gland is enlarging to compensate for decreased iodine in the body

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6
Q

most common cause of goiter

A

iodine deficiency

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7
Q

a condition where there is oversecretion of thyroid hormones

A

hyperthyroidism

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8
Q

an autoimmune disorder that causes hyperthyroidism

A

grave’s disease

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9
Q

components of grave’s disease

A

enlarged thyroid gland, exophthalmos, thyrotoxicosis

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10
Q

a term for s/sx of hyperthyroidism

A

thyrotoxicosis

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11
Q

another cause of hyperthyroidism caused by tumor

A

thyroid adenoma

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12
Q

manifestation of hyperthyroidism in weight

A

weight loss

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13
Q

manifestation of hyperthyroidism in CNS

A

irritability and restlessness

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14
Q

manifestation of hyperthyroidism in temperature

A

heat intolerance

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15
Q

hallmark of hyperthyroidism

A

heat intolerance

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16
Q

manifestation of hyperthyroidism in GIT

A

diarrhea

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17
Q

manifestation of hyperthyroidism in SNS

A

increased SNS = tachycardia, sweating, tremors

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18
Q

too much thyroid hormones will lead to

A

thyroid storm/crisis

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19
Q

s/sx of thyroid storm

A

tachyarrhythmias
hypertension
hyperthermia

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20
Q

what feedback mechanism will be activated if there is increased thyroid hormones?

A

negative feedback mechanism

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21
Q

what feedback mechanism will be activated if there is decreased thyroid hormones?

A

positive feedback mechanism

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22
Q

if thyroid hormones is increased, it will send signal to pituitary gland to decrease the TSH to decrease the thyroid hormones back to normal

A

negative feedback mechanism

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23
Q

if thyroid hormones is decreased, it will send signal to pituitary gland to increase the TSH to increase the hormones back to normal

A

positive feedback mechanism

24
Q

why do we measure the thyroid hormones level as well as the TSH?

A

to determine where is the problem

25
if the thyroid hormones are increased and the TSH is decreased, where is the problem?
thyroid gland - pituitary gland is functioning well bec. there is intact feedback mechanism but there is problem in thyroid gland
26
if the thyroid hormones and TSH are increased, where is the problem?
pituitary gland - no feedback mechanism
27
if the thyroid hormones are decreased and the TSH is increased, where is the problem?
thyroid gland - there is feedback mechanism
28
if both the thyroid hormones and TSH are decreased, where is the problem?
pituitary gland - no feedback mechanism
29
hyperfunctioning of thyroid gland will reveal what in the thyroid scan?
hotspots
30
hypofunctioning of the thyroid gland will reveal what in the thyroid scan?
cold spots
31
what does the thyroid ultrasound reveals?
if there is presence of tumor and if its cystic or solid
32
damage to laryngeal nerve during thyroidectomy may manifest
hoarseness of voice
33
diet for patients with hyperthyroidism
high protein, high caloric, high residue - fast metabolism
34
anti-thyroid drugs that dec. the synthesis of t3 and t4
propylthiouracil
35
adverse effect of PTU
hypothyroidism agranulocytosis
36
anti-thyroid drugs that dec. the synthesis of t3 from t4
methimazole carbimazole
37
anti-thyroid drugs that is being administered prior to surgery to dec. thyroid hormones as well as the hypervascularity of the gland
lugol's solution
38
a condition where there is undersecretion of thyroid hormones
hypothyroidism
39
an autoimmune disorder that causes hypothyroidism
hashimoto's thyroiditis
40
a condition that causes hypothyroidism as well as mental and physical retardation
cretinism
41
manifestation of hypothyroidism in CNS
forgetfulness, slowing of intellectual function
42
manifestation of hypothyroidism in GIT
constipation
43
manifestation of hypothyroidism in weight
weight gain
44
manifestation of hypothyroidism in SNS
decreased SNS = bradycardia, hypotension
45
manifestation of hypothyroidism in temperature
cold intolerance
46
hallmark of hypothyroidism
cold intolerance
47
cause of myxedema
accumulation of polysaccharides in the interstitial space due to dec. metabolism of carbohydrates
48
characteristics of myxedema
dry skin coarse and scaly skin brownish to yellowish skin
49
complication that may arise if myxedema accumulate in the heart
cardiogenic shock - heart becomes flabby
50
complication that may arise if myxedema accumulate in the brain
myxedema coma
51
manifestation of hypothyroidism in ECG
sinus bradycardia
52
manifestation of hyperthyroidism in ECG
sinus tachycardia
53
diet of patients with hypothyroidism
high fiber, low fat, low sugar, low cholesterol
54
drug replacement for hypothyroidism
levothyroxine levothyronine
55
when do you administer levothyroxine?
during morning