Thyroid Disease - Thyroid Eye Disease

Question 1

Pathophysiology of Thyroid Eye Disease.

Answer 1

TSH Receptor results in retro-orbital inflammation - glycosaminoglycan and collagen deposition in the muscles.

Question 2

Prevention of Thyroid Eye Disease (2).

Answer 2

1. Smoking - Most Important Modifiable Risk Factor.
2. Radioiodine Treatment increases inflammatory symptoms.

Question 3

Clinical Features of Thyroid Eye Disease (5).

Answer 3

1. Exophthalmos.
2. Conjunctival Oedema.
3. Optic Disc Swelling.
4. Ophthalmoplegia.
5. Sore, Dry Eyes - Exposure Keratopathy.

Question 4

Management of Thyroid Eye Disease (4).

Answer 4

1. Topical Lubricant - Keratitis.
2. Steroids.
3. Radiotherapy.
4. Surgery.