Thyroid cases (13) Flashcards
What are three metabolic conditions that can cause goiter?
- hypothyroidism
- hyperthyroidism
- euthyroidism
Does hyperthyroidism or hypothyroidism produce toxic goiter?
hyper
In Primary hyperthyroidism, what are the levels of:
- T4, T3
- TSH
- TRH
- High
- low
- low
In secondary hyperthyroidism, what are the levels of:
- T4, T3
- TSH
- TRH
- high
- high
- low
What causes graves disease?
TSH receptor antibodies
-thyroid stimulating – leads to hypertrophy of thyroid
What are four causes of hyperthyroidism?
- graves
- thyroid neoplasm
- exogenous T4, T3
- Excess TSH
What are four treatments for hyperthyroidism?
- PTU
- Thyroidectomy
- excessive Iodine
- B-adrenergic blocking agents - adjunct therapy
What does PTU do?
inhibits peroxidase enzyme - and thyroid hormone synthesis
In primary hypothyroidism, what are the levels of:
- T4, T3
- TSH
- TRH
- Low
- High
- High
In secondary hypothyroidism, what are the levels of:
- T4, T3
- TSH
- TRH
- low
- low
- high
What is hashimotos thyroiditis?
antithyroid antibodies which gradually destroy the gland
What is a key common symptom of hashimotos?
mixedema - nonpitting edema throughout
What group of people are particularly susceptible to hashimotos?
pregnant women - estrogen is really high so TBG binds T4
-decreases free amount
Does iodine increase or decrease synthesis of TG?
increase
What are some symptoms of hyperthyroidism?
- warm moist skin
- high BMR
- heart palpitations
- muscle wasting
- tachycardia
- heat intolerance
- tremor
- changes in hair growth and texture
- exopthalmus and eyelid retraction
What are symptoms of hypothyroidism?
- low BMR
- cold intolerance
- lethargy
- inc fat deposition
- hypotension
- nonpitting edema - mixedema
- skin changes
- headache
- constipation
What are five conditions that can cause hypothyroidism?
- hashimotos
- surgery
- Iodine deficiency
- congenital cretinism
- decreased TRH or TSH
What is the treatment for hypothyroidism in patients?
replacement therapy of thyroid hormones
What would be the only explanation for high T4, low TSH, and a small thyroid gland?
patient is taking exogenous thyroid extract
