Thyroid cancer Flashcards
What is the most common type of thyroid cancer?
Papillary
How does papillary cancer usually spread?
Lymph
What kind of thyroid cancer has an association with hashimotos thyroiditis?
Papillary
What type of cancer occurs mainly in the iodine rich parts of the thyroid gland?
Papillary
Which type of cancer commonly occurs in younger women?
Papillary
Which type of cancer is said to have orphan annie eyes on histology?
Papillary
How do you investigate for a suspected thyroid cancer?
US guided fine needle aspirate
Which type of cancer is commoner is people aged 40 - 60?
Follicular
Which type of cancer spreads haematogenously?
Follicular
Which type of cancer in commoner in areas where there is an iodine deficiency?
Follicular
What is the treatment for differentiated thyroid cancer?
Surgery
What biochemical test must be done 24 hrs after a thyroidectomy?
Calcium
What cancer arises from the parafollicular C cells?
Medullary
What cancer causes a rise in serum calcitonin?
Medullary
What are the two components of MEN2?
Medullary thyroid cancer + Phaeochromocytoma.
Which thyroid cancer do you get diarrhea in?
Medullary
What type of cancer occurs most often in elderly people?
Anaplastic
What type of cancer has the worst prognosis?
Anaplastic
How do you treat anaplastic thyroid cancer?
Palliative chemo and radio therapy
Which cancer has a very high mitotic rate?
Anaplastic
Which cancer is difficult to differentiate from a benign adenoma?
Follicular
Which cancer is derived from the epithelium?
Follicular
Which tyroid cancer is a neuroendocrine tumour?
Medullary
What serum tests is used to look for reccurrences of thyroid cancer?
Thyroglobulin
How high should the serum thyroglobulin be?
Less than 2
What else should the laboratory test for when they are testing for thyroglobulin?
Thyroglobulin antibodies
How long after a thyroidectomy should a patient get a radioisotope scan?
3 - 6 months
What does a patient have to do before getting a radio isotope scan to look for recurrence of thyroid cancer?
Stop taking T4 to cause a high TSH
How much uptake of iodine should the thyroid have after a whole body iodine scan?
Less than 0.1%
Where do parafollicular C cells come form embryologically?
The neural crest
How do you treat medullary thyroid cancer?
Surgery