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Endocrine (Zoe) > Hypothyroidism > Flashcards

Hypothyroidism Flashcards

1
Q

What antibodies are present in hashimotos thyroiditis?

A

Anti TPO

Anti thyroglobulin

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2
Q

What kind of goitre do you get in hashimtos thyroiditis?

A

Firm, non tender goitre

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3
Q

What kind of goitre do you get due to an iodine deficiency?

A

Non toxic multinodular goitre

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4
Q

What type of hypersensitivity reaction os hashimotos thyroiditis?

A

Type IV

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5
Q

What cardiac drug can cause hypothyroidism?

A

Amioderone

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6
Q

What is the initial treatment for hypothyroidism?

A

Thyroxine 50 - 100ug daily

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7
Q

How much does thyroixine dose need to be increased in prganancy?

A

25 - 50%

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8
Q

What is the initial dose of thyroixine for an elderly person who also has a histrory of heart disease?

A

Thyroxine 25 - 50ug daily

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9
Q

What marker do you use to monitor response to treatment for primary hypothyroidism?

A

TSH

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10
Q

What marker do you use to monitor response to treatment for secondary hypothyroidism?

A

T4

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11
Q

What psychiatric drug can cause hypothyroidism?

A

Lithium

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12
Q

What two immunological drugs can cause hypothyroidism?

A

Alpha interferon

IL2

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13
Q

How do you treat a myexodema coma?

A

IV levothyroxine (If no response within 24 hrs start IV T3)
IV hydrocortisone
Treat precipitating factors eg infection with antibiotics
Replace IV fluids and glucose as necessary
Slow warming to correct hypothermia

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14
Q

What should you do if you are considering starting levothyroxine but you think the patient has adrenal insufficiency?

A

Short synacthen test

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15
Q

What can thyroxine cause in patients with adrenal insufficiency?

A

Addisonian crisis

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16
Q

What respiratory manifestation can you get with hypothyroidism?

A

Pleural effusion

17
Q

What psychiatric complication can you get with hypothyroidism?

A

Dementia

18
Q

What cardiovascular complications can you get with hypothyroidism?

A

Pericardial effusion
Bradycardia
Low volume pulse

19
Q

What peripheral nervous system problems can you get with hypothyroidism?

A

Carpal tunnel syndrome

Proximal mypathy

20
Q

Are cholesterol levels high or low in hypothyroidism?

A

High

21
Q

Where abouts does hairloss occur in hypothyroidism?

A

lateral third of the eyebrow

22
Q

What is sick euthyroid syndrome?

A

There is a low T3/T4 but the thyroid gland doesn’t appear to be disfunctional and there is a normal TSH

23
Q

In what situations might you get sick euthyroid syndrome?

A

Intensive care

Starvation

Endocrine (Zoe) (12 decks)

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