Thyriod Flashcards
Normal TSH T3 and T4 levels
TSH = .4-5.5 T3 = 80-220 T4 = .7-2.0
Thyroid nodules
If visibile - hyperthyroid
Can be uncomfortable
Obstructive sx - sob, hoarness, dyspaghia, sob
Concern if pressing on the laryngeal nerve
Thyroid nodule concerning features
Rapid growth, solid nodule, hard and fixed , esophageal or tracheal obstruction , swelling under jaw
Thyroid nodules - what to do with them
Assess for thyroid function - TSH and T4
Low TSH - nodule is producing thyroid hormone
High TSH - autoimmune inflammation of the thyroid ( hashimotos)
Thyroid US
Can assess # of nodules, location and size
Can tell if it is cystic solid
But not diagnostic
Thyroid scan
Uses a radioactive substance to determine the nodule function
Cold = non function and needs biopsy Hot = not concern for CA
FNA
Biopsy
In office, 5-6 samples, may miss the area
Takes 2-3 weeks to come back
Thyroid Cancer
Risks : childhood ca, ages 30-60 M>W, radiation exposure, fam hx
ROS: hoarness and dysphagia
DX; elevated TSH , cold nodules
Management : scans every 3-6 months x 5 years after diagnosis
Scans 6-12 months once cancer free
Goiter
Pronounced swelling of neck
Common in hashimotos
Hyperthyroidism
decrease in TSH increase in T3 - excess thyroid hormone May be due to graves Inflammation of thyroid gland Excessive intake of thyroxine mediation Excess TSH from pituitary glan
Hyper s/s
Increased metabolic rate
Intolerance to heat
Fine, straight hair, bulging eyes, tachy increased BP, tachy, tremors, weight loss, amenorrhea
Agitation, racing HR
Hyper labs
Low TSH and increased T3 , t4 , free t5
Hyper TX
Radiation , medication , or surgery
- methimazole - 3 divided doses 8 hour internals
- PTU - TID good for pregnant women
- treament may be life long
- beta blocker to decrease HR
- metabolism return to normal 1 -2 months
Hypothyroidism
Caused by hashimotos
Increased TSH decreased T4
Hypo s/s
Early = hair loss, dry skin, contsptiaion , intolerance to cold, thick tongue
Late- Brady, weight gain, decreased loc, thickend skin, cardiac complications
PE: facial puffiness, goiter, enlarged tongue, depression, dementia , diminished reflexes, coarse hair, brittle nail, yellow hue, dryness, weight gain