thrombotic thrombocytopenia purpura Flashcards
1
Q
what is TTP?
A
genetic or acquired deficiency of ADAMTS13
with characteristic rich-von Willebrand factor microthrombi affecting the arterioles and capillaries of multiple organs.
2
Q
what is the pentad of TTP which normally affects adult females?
A
fever
CNS signs- confusion, seizures
MAHA- Microangiopathic hemolytic anemia
thrombocytopenia
renal failure