thrombotic thrombocytopenia purpura Flashcards

1
Q

what is TTP?

A

genetic or acquired deficiency of ADAMTS13

with characteristic rich-von Willebrand factor microthrombi affecting the arterioles and capillaries of multiple organs.

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2
Q

what is the pentad of TTP which normally affects adult females?

A

fever
CNS signs- confusion, seizures
MAHA- Microangiopathic hemolytic anemia
thrombocytopenia
renal failure

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