Thrombotic Microangiopathy Flashcards
1
Q
hemolytic uremic syndrome
A
diarrhea-associated, endotoxin A, “glomerular paralysis”
2
Q
atypical hemolytic uremic syndrome
A
auto-antibody against complement (CFH, CFI, MPC); treat with eculizumab
3
Q
thrombotic thrombocytopenia purpura
A
ADAMST13 mutation, familial/acquired, CNS involvement
4
Q
antiphospholipid antibody syndrome
A
livido reticularis, spontaneous abortions, ANA+; ischemic wrinkling
5
Q
malignant hypertension
A
secondary HTN to renal artery stenosis, granular surface (gross path)
6
Q
renal artheroembolic disease
A
after cardiac intervention, with rash and eosinophilia
