BP Variations Flashcards
1
Q
glucocorticoid remediated aldosteronism
A
autosomal dominant; low renin, high aldo
2
Q
apparent mineral corticoid excess syndrome
A
absence of 11B HSD; low renin, low aldo, high urine cortisol
3
Q
excess licorice consumption
A
glycyrrhizic acid, inhibits 11B HSD
4
Q
adrenal adenoma
A
low renin, high aldo; Cushing, CONN
5
Q
primary aldosteronism
A
KCNJ5 mutation; K-channel permeable to Na
6
Q
renal artery stenosis
A
fibromuscular dysplasia, artherosclerosis
7
Q
pheochromacytoma
A
adrenal gland tumor, episodic HTN + triad (headaches, sweatiness, palpitations) [secondary cause: cocaine use]
8
Q
Barter syndrome
A
NKCC2 transporter in TALH; hypotension, hyokalemia, metabolic alkalosis
9
Q
Gittelman syndrome
A
NCCT transporter DCT; hypotension, hypokalemia, metabolic alkalosis (asymptomatic)
