Thrombosis and Embolism Flashcards
What is the term for normal blood flow?
Laminar
What is the term for stagnant blood flow?
Stasis
What is the term for unpredictable forceful flow?
Turbulance
What are the 2 main causes for problems in blood flow?
Thromboembolism
Atheroma
What is Virchow’s triad?
A group of 3 main factors that cause thrombosis
What are the 3 factors involved in Virchow’s triad?
Changes in blood vessel wall
Changes in blood constituents
Changes in blood flow patern
What is thrombosis?
The formation of a solid mass formed from blood constituents within the vascular system
What is the main cause for changes in the blood vessel wall?
Atheroma
What is a common cause for changes in the blood flow constituents?
Hypercholesterolaemia
What are 3 common clinical conditions related to thrombosis?
DVT (deep venous thrombosis)
Ischemic limb
MI
What is recanalisation?
The process of restoring blood flow to normal
What can propogation (spreading) of thrombosis lead to?
An embolism
What is an embolism?
The movement of abnormal material in the blood stream and impact in a vessel
What is an embolus?
A detached intravascular mass
What are the 2 types of thromboembolus?
Arterial & venous
Where do venous thromboemboli originate from?
Lower limbs (deep venous thromboses)
Where do venous thromboemboli travel to>
The pulmonary arterial circulation
What are 3 consequences of pulmonary thromboemboli?
Pulmonary infarction
Pulmonary hypertension
Right ventricular failure
What are 2 social risk factors for DVT and pulmonary thromboembolism?
Increased age
Obesity
When do fat emboli appear?
After major fractures
What 3 organs can fat emboli affect?
Brain
Kidneys
Skin
What is decompression sickness?
When N2 formed from rapid decompression lodge in the capi;;aroes
What are 2 causes of air emboli?
Head and neck wounds
Surgery
What type of emboli could be found in a pregnant woman’s lungs?
Trophoblasts
What type of embolus is infective endocarditis related to?
Septic material
What type of embolus can be caused by childbirth?
Amniotic fluid
What embolus can be found after bone fractures?
Bone marrow