Infective Endocarditis Flashcards
What is infective endocarditis?
An infection of the endocardium (inner layer of heart)
What 3 areas of the heart can infective endocarditis affect?
Heart valves
Interventricular septum
Chordae tendinae
What are 2 cardiac predispositions for infective endocarditis?
Rheumatic heart disease
Valvular heart diseases
What are 3 non-cardiac predispositions for infective endocarditis?
Diabetes
AIDS
Meningitis
What are 4 lifestyle risk factors for infective endocarditis?
Injected drug use
Alcohol
Pet exposure
Old age
What are 4 signs of infective endocarditis?
Fever
Weight loss
Headache
Musculoskeletal pain
What are 3 signs of infective endocarditis on examination?
Murmur
Splinter haemorrhages
Vasculitic rash
What 4 blood tests can be done to help identify infective endocarditis?
FBC
CRP (C-reactive protein)
ESR (erythrocyte sedimentation rate)
Blood cultures
What are 3 scans that can be done to help identify infective endocarditis?
ECG
CXR
ECHO
What are the 3 types of bacteria you would expect to find on a blood culture if the patient had infective endocarditis?
Staphylococci (staph aureus)
Streptococci
Enterococci
If a blood culture is positive for bacteria involved in infective endocarditis what treatment is given if it is affecting Native Valves? (2)
Gentamicin and amoxycillin
If a blood culture is positive for bacteria involved in infective endocarditis what treatment is given if it is affecting Native Valves AND Sepsis? (2)
Gentamicin and Vancomycin (intravenously)
If a blood culture is positive for bacteria involved in infective endocarditis what treatment is given if it is affecting Prosthetic Valves? (3)
Gentamicin, Vancomycin (intravenously) and Rifapicin
What are 4 complications of infective endocarditis that can be indications for surgery?
Heart failure Fistula formation Leaflet perforation Uncontrolled infection Abscess formation AV heart block Embolism Prosthetic valve dysfunction
What treatment should be given to highest risk infective endocarditis patients?
Antibiotic prophylaxis