Thrombolytics/fibronolytics Flashcards

1
Q

What is an example of a Tissue Plasminogen Activators (TPAs)

A

Alteplase

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2
Q

What does alteplase do for an AMI?

A

It lyses coronary artery thrombi

less common use

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3
Q

What does alteplase do for ports and catheters?

A

It lyses occluded ports and catheters

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4
Q

What is the MC use for alteplase?

A

Management of ischemic stroke

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5
Q

What is the stroke dose for alteplase??

A

0.9 mg/kg

Max 90 mg

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6
Q

How is alteplase administered for a stroke?

A

Load dose of 0.09 mg/kg (10% of total dose) over 1 minute

Follow w/ 0.81 mg/kg (90% of dose) CIV over 1 hour

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