Thrombolytics/fibronolytics Flashcards
1
Q
What is an example of a Tissue Plasminogen Activators (TPAs)
A
Alteplase
2
Q
What does alteplase do for an AMI?
A
It lyses coronary artery thrombi
less common use
3
Q
What does alteplase do for ports and catheters?
A
It lyses occluded ports and catheters
4
Q
What is the MC use for alteplase?
A
Management of ischemic stroke
5
Q
What is the stroke dose for alteplase??
A
0.9 mg/kg
Max 90 mg
6
Q
How is alteplase administered for a stroke?
A
Load dose of 0.09 mg/kg (10% of total dose) over 1 minute
Follow w/ 0.81 mg/kg (90% of dose) CIV over 1 hour