Third Year Buzzwords Flashcards
thunderclap headache
subarachnoid haemorrhage
xanthochromic lumbar puncture
subarachnoid haemorrhage
lucid period after head trauma then deterioration
extradural haemorrhage
lemon/convex shaped bleed on CT
extradural haemorrhage
low impact trauma in elderly person/alcoholic
subdural haemorrhage
banana/crescent shaped bleed on CT
subdural haemorrhage
cogwheel rigidity
Parkinsons disease
positive Gowers manoevure
muscular dystrophy
REM sleep disturbance
Lewy body dementia
personality changes followed by dementia
fronto-temporal dementia
4 main symptoms of Parkinson’s
T - tremor
R - rigidity
A - ataxia (bradykinesia)
P - postural instability
dementia with stepwise deterioration
vascular dementia
weakness + frontal balding + cataracts + ptosis
myotonic dystrophy
positive Babinski’s sign
UMN lesion
pronator drift
UMN lesion
antipsychotic causing agranulocytosis
clozapine
syndrome due to thiamine deficiency
Wernickes Korsakoff syndrome
painless maternal blood with no foetal distress
placenta praevia
foetal blood + sudden foetal distress
vasa praevia
PPH followed by pituitary failure
Sheenan’s syndrome
pleural effusion + ascites + ovarian thecoma
Meig’s syndrome
foetal distress + loss of engagement
uterine rupture
chocolate cysts in ovary
endometrioma
strawberry cervix
trichomonas vaginalis
clue cells, vaginal pH >4.5
bacterial vaginosis
large, tense uterus with woody abdomen
bleeding and pain
placental abruption
ADHD triad of symptoms
hyperactivity
impulsivity
inattention
autism triad of symptoms
impaired communication
language
repetitive behaviour
pepper pot skull/lytic bone lesions
myeloma
congo red staining
amyloid deposits in myeloma or AA amyloidosis
Reed-Sternberg cells
Hodgkin Lymphoma
alcohol causes pain in this haem cancer
Hodgkin Lymphoma
snowstorm appearance on USS
molar pregnancy
overly high HCG and SFH large for gestational age
molar pregnancy
first line anti-emetic for hyperemesis
cyclising or prochloperamide
Philadelphia chromosome translocation
chronic myeloid leukaemia
Auer rods
acute myeloid leukaemia
bence jones protein
multiple myeloma
itchy after bath
polycythaemia vera
deficiency in factor XIII
haemophilia A
deficiency in factor IX
haemophilia B
smudge cells (immature leukocytes)
chronic lymphocytic leukaemia
schistocytes
intravascular haemolysis
Howel Jolly bodies
hyposplenism
Bell’s palsy - UMN or LMN
LMN
features of Bell’s palsy
facial droop sagging of mouth on smiling loss of forehead wrinkling reduced taste hypersensitivity to sound
dementia presenting with short term memory loss
Alzheimer’s
gait disturbance + urinary incontinence in stepwise progression
vascular dementia
REM sleep disorders + visual hallucinations + fluctuating cognitive ability
Lewy body dementia
changes in pre-morbid personality initially
fronto-temporal dementia
management of dementia initially
cholinesterase inhibitors - donepezil, rivastigmine
example of NMDA receptor antagonist
memantine
fluency of speech is maintained but is non-sensical
receptive aphasia/Wernicke’s aphasia
comprehension is intact/speech makes sense but is staggered and effortful
expressive aphasia/Broca’s aphasia
pinpoint pupils, appears snoring/sleeping
opioid overdose
acute management of opioid overdose
naloxone
dilated pupils, n&v, tachycardia, lacrimation, piloerection
opioid withdrawal
drug to reduce long term cravings of alcohol, commenced once out of withdrawal
naltrexone
inhibitor of acetaldehyde dehydrogenase for alcohol dependency
Antabuse
differentiating features of MG and LEMS
LEMS - fatigue improves as day goes on, also has autonomic features and hyporeflexia
autoantibodies against the post-synaptic ACh terminal
myasthenia gravis
pes cavus, champagne legs, weakness and peripheral sensory loss
Charcot-Marie tooth disease
triggers for GBS
campylobacter
CMV
EBV
fluent speech, comprehension intact, repetition poor
conductive dysphasia
tear drop RBCs
myelofibrosis
spherocytes
hereditary spherocytosis
schistocytes
haemolytic anaemia
Heinz bodies
denatured haemoglobin eg G6PD def
most common pathogens causing viral meningitis
ECHO virus
enterovirus (coxsackie)
herpes simplex
most common pathogens causing bacterial meningitis
strep pneumoniae
neisseria meningitis
most common pathogens causing bacterial meningitis in neonates
listeria
group B strep
E. coli
most common pathogens causing bacterial meningitis in children under 10
haemophilus influenza
most common pathogens causing bacterial meningitis in elderly people
listeria monocytogenes
who is most likely to get fungal meningitis
HIV/immunocompromised people
typically cryptococcal
contraindications for lumbar puncture
papilloedema focal neurology vomiting altered consciousness GCS <9
LP for viral meningitis shows
mainly lymphocytes
LP for bacterial meningitis shows
mainly neutrophils
first line treatment for bacterial meningitis
IV ceftriaxone
what is added to Abs for an elderly patient with meningitis
amoxicillin for cover against listeria
what are the components of triple assessment
clinical history/exam
imaging
biopsy
firm, mobile, simple breast lump
fibroadenoma
management of VTE in pregnancy
low molecular weight heparin
causes of SGA baby
constitutionally small
IUGR
prematurity
causes of LGA baby
polyhydramnios
multiple pregnancy
macrosomia
wrong dates
4 Ts of PPH
tone
tissue
trauma
thrombin
example of tocolytic
terabutaline
management of shoulder dystocia
H - help E - evaluate for episiotomy L - legs McRoberts manoeuvre P - pressure suprapubically E - enter the pelvic R - get mother to roll
SSRI that is safe in pregnancy and one that is not safe
sertraline - safe
paroxetine - unsafe
lithium causes which foetal anomaly
cardiac defects - Epstein’s anomaly
Benzes cause what foetal anomaly
cleft lip
neonatal withdrawal
triad of congenital rubella syndrome
eye problems - cataract, glaucoma etc
sensorineural hearing loss
cardiac defects
are NSAIDs safe in pregnancy
no - cause closure of ductus arteriosus and prevent the cervix from ripening in labour as prostaglandins are blocked
components of combined test for Down’s
USS to assess nuchal thickness >6mm
bloods - bHCG and PAPP-A
raised or lowered bHCG and PAPP-A are suggestive of Down’s
bHCG - raised
PAPP-A - lowered
when is the triple test to assess for Down’s carried out
14-20 weeks
components of triple test
bHCG + AFP and serum oestradiol
components of quadruple test
bHCG + AFP + serum oestradiol + inhibin-A
two options for antenatal diagnostic testing for Down’s
CVS - 11-14 weeks
amniocentesis - from 15 weeks
which antihypertensives are safe to use in pregnancy
labetolol
methyldopa
nifedipine
TAILS pneumonic for microcytic anaemia
thalassaemia anaemia of chronic disease iron deficiency lead poisoning sideroblastic anaemia
painful lymph nodes after drinking
Hodgkin’s lymphoma
B symptoms in lymphoma
fever
night sweats
weight loss
diagnostic test for blood cancers
immunophenotyping
what type of drug is Rituximab and what is it used to treat
anti-CD20 monoclonal Ab - used to treat Non-Hodgkin’s lymphoma
blood film with Roulex formation
paraprotein disease
4 main types of myeloproliferative disorders
polycythaemia rubra vera
essential thrombocythaemia
chronic myeloid leukaemia
myelofibrosis
JAK 2 mutation causes
polycythaemia rubra vera
itchy after a hot bath
polycythemia rubra vera
VWF disease will have prolonged aPTT or PTT
aPTT
management of VWD disease
desmopressin, promotes the release of VWF
factor 8 deficiency
haemophilia A
where is B12 absorbed
terminal ileum
where is folate absorbed
duodenum