Thiazide Medications

Question 1

What medications could have caused hyponatraemia?

Answer 1

Bendroflumethiazide

Question 2

Thiazide diuretics can cause……… , because

Answer 2

hypercalcaemia and hypocalciuria

Question 3

Side effects of thiazide medications?

Answer 3

dehydration
postural hypotension
hypokalaemia
due to increased delivery of sodium to the distal part of the distal convoluted tubule → increased sodium reabsorption in exchange for potassium and hydrogen ions
hyponatraemia
hypercalcaemia
the flip side of this is hypocalciuria, which may be useful in reducing the incidence of renal stones
gout
impaired glucose tolerance
impotence