thertiary structure- what are domains Flashcards

1
Q

Domains

A

Lobal structures with about 100-200 amino acids, they are structurally independent with characteristics of small globular proteins and have specific functions

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1
Q

example of domain functions

A

catalytic domain, regulatory domain, domain for binding a cofactor, binds substrate initially, then pass it to a different domain

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2
Q

domain categories

A

alpha (helices), beta(sheets), alpha/beta(both), few secondary structures

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3
Q

alpha/beta

A

good for making globular proteins

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4
Q

alpha/beta barrels

A
  • most common in enzymes
  • really good scaffolding of active site
  • has active sits formed by loops from c teriminus, and ends of b-strands
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5
Q

b-sheet twist

A

twisting is a result of L-amino acidds

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6
Q

Rossman fold

A

a type of protein topology (the order in which secondary structural features are connected in the protein main chain) with alpha/beta/alpha secondary structures
- binds nucleotides and their derivatives

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