Therapeutics - Upper GI tract Flashcards
1
Q
Give examples of H2 Receptor Antagonists
A
Ranitidine and Cimetidine
2
Q
How do H2 Receptor Antagonists work?
A
3
Q
What are the 3 drugs that can be used to treat GORD in order of effectiveness?
A
antacids
H2 receptor antagonist
proton pump inhibitors
4
Q
Give some examples of proton pump inhibitors
A
Omeprazole and Lansoprazole
5
Q
What are some common causes of gastric ulcers?
A
H. pylori - 50%
NSAIDs - 30%
Carcinoma - 5%
Others:
- neoplasia
- Crohn’s
- stress
ZE Syndrome
6
Q
How can a H. pylori infection be diagnosed?
A
urea breath test
stool antigen
serology
7
Q
How is a H. pylori infection treatment?
A
3,2,1 strategy
3 drugs - proton pump inhibitor and two antibiotics
2 - twice a day
1 week
8
Q
What are some known risk factors for GORD?
A
being overweight
being pregnant
eating a high-fat diet
9
Q
A
