Therapeutic Cytokines and Antibodies Flashcards
What is aldesleukin?
IL-2, used in renal cell cx, metastatic melanoma
What is epoetin-a?
EPO, used in anemia
What is filgastim?
G-CSF for bone marrow recovery
What is Sargramostim?
GM-CSF for bone marrow recoery
What is a-interferon?
For active HBV, HCV, Kaposi,
What is b-interferon?
MS
What is g-interferon?
used in CGD
What is oprelvekin?
IL-1, used in thrombocytopenia
What is thrombopoeitin?
used in thrombocytopenia
What is used in digoxin overdose?
Digoxin immune Fab
What is Infliximab?
Anti-TNF-a used in Crohn’s, RA, psoriatic arthritis, ankylosing spondylitis
What is Adalimumab?
Anti-TNF-a used in Crohn’s, RA, psoriatic arthritis, ankylosing spondylitis
What is Abciximab?
Anti GpIIb/IIIa that prevents platelet aggregation.
Used to prevent cardiac ischemia inunstalbe angina
What is Trastuzumab?
Anti-HER2 used in Her2 expressing breast cancers
What is Rituximab?
Anti-CD-20 used un B-cell non-Hodgkin’s lymphoma